Characterization of salA, syrF, and syrG Genes and Attendant Regulatory Networks Involved in Plant Pathogenesis by Pseudomonas syringae pv. syringae B728a. [PDF]
Pseudomonas syringae pv. syringae B728a, causal agent of brown spot on bean, is an economically important plant pathogen that utilizes extracellular signaling to initiate a lifestyle change from an epiphyte to a pathogen. LuxR regulatory proteins play an
Vanessa L Vaughn, Dennis C Gross
doaj +1 more source
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun +10 more
wiley +1 more source
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp. [PDF]
BACKGROUND: Many bacteria, including Vibrio spp., regulate virulence gene expression in a cell-density dependent way through a communication process termed quorum sensing (QS). Hence, interfering with QS could be a valuable novel antipathogenic strategy.
Gilles Brackman +7 more
doaj +1 more source
A Spontaneous Mutation in tfoX Impairs Bioluminescence in Photobacterium kishitanii ANT‐2200
A frameshift mutation in tfoX generates a truncated regulator associated with reduced lux–rib expression and low luminescence. Complementation with wild‐type tfoX restores transcription and light production, supporting a role for TfoX in regulating bioluminescence independently of quorum sensing.
Capucine Le Cam Ligier +6 more
wiley +1 more source
We report a novel hierarchical regulatory circuit consisting of two MarR‐family transcription factors, OhrR and EmrR, that act antagonistically to dynamically fine‐tune the Vfm QS system and bacterial virulence. ABSTRACT Rice foot rot, caused by Dickeya oryzae, is a destructive bacterial disease.
Wenqi Huang +7 more
wiley +1 more source
From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño +9 more
wiley +1 more source
Role of the LuxR solo, SdiA, in eavesdropping on foreign bacteria
Abstract Bacteria can cooperate by coordinating their gene expression through the production, release, and detection of small molecules, a phenomenon known as quorum sensing (QS). One type of QS commonly found in Gram-negative bacteria utilizes a LuxI-type enzyme to produce a signaling molecule of the N-acyl-homoserine lactone (AHL ...
Andrew Schwieters, Brian M M Ahmer
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Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors.
Quorum sensing is a typical communication system among Gram-negative bacteria used to control group-coordinated behavior via small diffusible molecules dependent on cell number.
Sophie Brameyer, Ralf Heermann
doaj +1 more source
Natural Lactone‐Based Quorum Sensing Inhibitors Attenuate Virulence in Pseudomonas aeruginosa
Targeting bacterial communication, lab‐generated lactones (Lx) inhibited biofilm formation and eliminated mature biofilms within 24–48 h. Lx treatment also suppressed pyocyanin and rhamnolipid production while downregulating rhlR expression, highlighting their promise as potent quorum‐sensing (QS) inhibitors and next‐generation antibiofilm therapeutics.
Shivani Chaturvedi +5 more
wiley +1 more source
LuxR Solos in the Plant Endophyte Kosakonia sp. Strain KO348
Cell-cell signaling in bacteria allows a synchronized and coordinated behavior of a microbial community. LuxR solos represent a subfamily of proteins in proteobacteria which most commonly detect and respond to signals produced exogenously by other microbes or eukaryotic hosts.
Mosquito Susan +9 more
openaire +3 more sources

