Results 71 to 80 of about 6,958 (200)
Expression and Quorum Sensing Regulation of Type III Secretion System Genes of Vibrio harveyi during Infection of Gnotobiotic Brine Shrimp. [PDF]
PLoS ONE, 2015 Type III secretion systems enable pathogens to inject their virulence factors directly into the cytoplasm of the host cells. The type III secretion system of Vibrio harveyi, a major pathogen of aquatic organisms and a model species in quorum sensing ...
H A Darshanee Ruwandeepika +3 more
doaj +1 more source
Molecular Microbiology, EarlyView.LexR1 is a LuxR‐type regulator that links nutrient sensing to effector gene expression in Legionella. Activated by a casamino acid‐derived ligand, LexR1 directly controls multiple effector genes using a conserved regulatory element present in numerous putative effectors across different Legionella species.
Chen Adler, Gil Segal
wiley +1 more source
A Spontaneous Mutation in tfoX Impairs Bioluminescence in Photobacterium kishitanii ANT‐2200
Molecular Microbiology, EarlyView.A frameshift mutation in tfoX generates a truncated regulator associated with reduced lux–rib expression and low luminescence. Complementation with wild‐type tfoX restores transcription and light production, supporting a role for TfoX in regulating bioluminescence independently of quorum sensing.
Capucine Le Cam Ligier +6 more
wiley +1 more source
DataSheet1_Computer-Aided Rational Engineering of Signal Sensitivity of Quorum Sensing Protein LuxR in a Whole-Cell Biosensor.docx [PDF]
, 2021 LuxR, a bacterial quorum sensing-related transcription factor that responds to the signaling molecule 3-oxo-hexanoyl-homoserine lactone (3OC6-HSL). In this study, we employed molecular dynamics simulation and the Molecular Mechanics Generalized Born ...
Ruifu Yang (46412) +12 more
core +1 more source
Characterization of salA, syrF, and syrG Genes and Attendant Regulatory Networks Involved in Plant Pathogenesis by Pseudomonas syringae pv. syringae B728a. [PDF]
PLoS ONE, 2016 Pseudomonas syringae pv. syringae B728a, causal agent of brown spot on bean, is an economically important plant pathogen that utilizes extracellular signaling to initiate a lifestyle change from an epiphyte to a pathogen. LuxR regulatory proteins play an
Vanessa L Vaughn, Dennis C Gross
doaj +1 more source
Protein Science, Volume 35, Issue 8, August 2026.Abstract Microorganisms use diverse small‐molecule signals to coordinate behavior, supporting interspecies and interkingdom communication. These chemical dialogs shape fundamental biological processes and define interactions from cooperation to antagonism.
Dor Ben Tovim +4 more
wiley +1 more source
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp. [PDF]
PLoS ONE, 2011 BACKGROUND: Many bacteria, including Vibrio spp., regulate virulence gene expression in a cell-density dependent way through a communication process termed quorum sensing (QS). Hence, interfering with QS could be a valuable novel antipathogenic strategy.
Gilles Brackman +7 more
doaj +1 more source
Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Directed evolution of the autoinducer selectivity of Vibrio fischeri LuxR.
The Journal of general and applied microbiology, 2016 LuxR family transcriptional regulators are the core components of quorum sensing in Gram-negative bacteria and exert their effects through binding to the signaling molecules acyl-homoserine lactones (acyl-HSLs). The function of the LuxR homologs is remarkably plastic, and naturally occurring acyl-HSLs are structurally diverse.
Tashiro, Yohei +7 more
openaire +2 more sources
An Experimentally Verified Mechanistic Model for Predicting Quorum Sensing‐Based Switches
Microbial Biotechnology, Volume 19, Issue 7, July 2026.A predictive model was developed to fine‐tune EsaI/EsaR quorum sensing circuits, highlighting the transcription factor's pivotal role and offering a foundation for broader applications across LuxR‐family systems in synthetic biology. ABSTRACT Quorum sensing‐based genetic circuits are gaining traction in synthetic biology as they link population‐level ...
Jasmine De Baets +2 more
wiley +1 more source