Results 31 to 40 of about 11,555 (204)
Fishes, 2023 This study aimed to investigate the effect of reduced expression of the luxR gene on the virulence of Pseudomonas plecoglossicida and the immune response of Epinephelus coioides. To achieve this, RNA interference (RNAi) was used to silence the luxR gene,
Lingmin Zhao +6 more
doaj +1 more source
Marine Drugs, 2019 Atratumycin is a cyclodepsipeptide with activity against Mycobacteria tuberculosis isolated from deep-sea derived Streptomyces atratus SCSIO ZH16NS-80S.
Zhijie Yang +5 more
doaj +1 more source
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover [PDF]
Microbiology, 2002 N-acyl-L-homoserine lactones (AHLs) are co-regulatory ligands required for control of the expression of genes encoding virulence traits in many Gram-negative bacterial species. Recent studies have indicated that AHLs modulate the cellular concentrations of LuxR-type regulatory proteins by binding and fortifying these proteins against proteolytic ...
Manefield, Michael +6 more
openaire +2 more sources
Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics [PDF]
, 2018 The proteobacteria Variovorax sp. WDL1, Comamonas testosteroni WDL7, and Hyphomicrobium sulfonivorans WDL6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron.
Anders +52 more
core +2 more sources
Prediction by promoter logic in bacterial quorum sensing. [PDF]
PLoS Computational Biology, 2012 Quorum-sensing systems mediate chemical communication between bacterial cells, coordinating cell-density-dependent processes like biofilm formation and virulence-factor expression.
Navneet Rai +6 more
doaj +1 more source
Biosensors, 2021 Aliivibrio fischeri LuxR and Aliivibrio logei LuxR1 and LuxR2 regulatory proteins are quorum sensing transcriptional (QS) activators, inducing promoters of luxICDABEG genes in the presence of an autoinducer (3-oxo-hexanoyl-l-homoserine lactone).
Sergey Bazhenov +7 more
doaj +1 more source
LuxR-family ‘solos’: bachelor sensors/regulators of signalling molecules [PDF]
Microbiology, 2009 N-Acylhomoserine lactone (AHL) quorum-sensing (QS) signalling is the best-understood chemical language in proteobacteria. In the last 15 years a large amount of research in several bacterial species has revealed in detail the genetic, molecular and biochemical mechanisms underlying AHL signalling. These studies have revealed the role
Sujatha Subramoni, Vittorio Venturi
openaire +3 more sources
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core +1 more source
Frontiers in Microbiology, 2022 Quorum sensing (QS) is a bacterial cell-cell communication system with genetically regulated mechanisms dependent on cell density. Canonical QS systems in gram-negative bacteria possess an autoinducer synthase (LuxI family) and a transcriptional ...
Martha Patricia Chávez-Moctezuma +6 more
doaj +1 more source
Binding mode exploration of LuxR-thiazolidinedione analogues, e-pharmacophore-based virtual screening in the designing of LuxR inhibitors and its biological evaluation [PDF]
Journal of Biomolecular Structure and Dynamics, 2016 Master quorum sensing (QS) regulator LuxR of Vibrio harveyi is a unique member of the TetR protein superfamily. Recent studies have demonstrated the contribution of thiazolidinedione analogues in blocking QS by decreasing the DNA-binding ability of LuxR. However, the precise mechanism of thiazolidinedione analogues binding to LuxR is still unclear.
Sundaraj, Rajamanikandan +2 more
openaire +2 more sources