Results 21 to 30 of about 11,555 (204)

Orphan LuxR regulators of quorum sensing [PDF]

FEMS Microbiology Reviews, 2009
Bacteria can modulate their behavior by releasing and responding to the accumulation of signal molecules. This population co-ordination, referred to as quorum sensing, is prevalent in Gram-negative and Gram-positive bacteria. The essential constituents of quorum-sensing systems include a signal producer, or synthase, and a cognate transcriptional ...
Arati V, Patankar, Juan E, González
openaire   +2 more sources

Interactions among quorum sensing inhibitors. [PDF]

PLoS ONE, 2013
Many pathogenic bacteria use quorum sensing (QS) systems to regulate the expression of virulence genes in a density-dependent manner. In one widespread QS paradigm the enzyme LuxI generates a small diffusible molecule of the acyl-homoserine lactone (AHL)
Rajat Anand, Navneet Rai, Mukund Thattai
doaj   +1 more source

Computer-Aided Rational Engineering of Signal Sensitivity of Quorum Sensing Protein LuxR in a Whole-Cell Biosensor

Frontiers in Molecular Biosciences, 2021
LuxR, a bacterial quorum sensing-related transcription factor that responds to the signaling molecule 3-oxo-hexanoyl-homoserine lactone (3OC6-HSL). In this study, we employed molecular dynamics simulation and the Molecular Mechanics Generalized Born ...
Jinyu Li, Jinyu Li, Ruicun Liu, Yulu Chen, Shuxia Liu, Cheng Chen, Tuoyu Liu, Shan Yang, Yingtan Zhuang, Yingtan Zhuang, Ruifu Yang, Yujun Cui, Yajun Song, Tao Wang, Yue Teng   +14 more
doaj   +1 more source

Intragenic suppression of a mutation: Characterization of an autoinducer-independent LuxR [PDF]

FEMS Microbiology Letters, 1995
The Vibrio fischeri luminescence genes are activated by the LuxR protein and a diffusible signal termed the autoinducer. LuxR consists of two domains, a C-terminal transcriptional activator domain, and an N-terminal autoinducer-binding domain, which serves to regulate the function of the C-terminal domain.
K A, Poellinger, J P, Lee, J V, Parales, E P, Greenberg   +3 more
openaire   +2 more sources

LitR directly upregulates autoinducer synthesis and luminescence in Aliivibrio logei [PDF]

PeerJ, 2021
LitR is a master-regulator of transcription in the ainS/R and luxS/PQ quorum sensing (QS) systems of bacteria from Vibrio and Aliivibrio genera. Here, we for the first time directly investigated the influence of LitR on gene expression in the luxI/R QS ...
Sergey Bazhenov, Olga Melkina, Vadim Fomin, Ekaterina Scheglova, Pavel Krasnik, Svetlana Khrulnova, Gennadii Zavilgelsky, Ilya Manukhov   +7 more
doaj   +2 more sources

Modeling Analysis of Signal Sensitivity and Specificity by Vibrio fischeri LuxR Variants. [PDF]

PLoS ONE, 2015
The LuxR protein of the bacterium Vibrio fischeri belongs to a family of transcriptional activators that underlie pheromone-mediated signaling by responding to acyl-homoserine lactones (-HSLs) or related molecules. V. fischeri produces two acyl-HSLs, N-3-
Deanna M Colton, Eric V Stabb, Stephen J Hagen   +2 more
doaj   +1 more source

CsrA modulates luxR transcript levels in Vibrio fischeri [PDF]

FEMS Microbiology Letters, 2012
The quorum-sensing and CsrA regulons of Vibrios control overlapping cellular functions during growth. Hence, the potential exists for regulatory network interactions between the pathways that enable them to be coordinately controlled. In Vibrio cholerae, CsrA indirectly modulates the activity of LuxO in the quorum-sensing signaling pathway.
Joshua W, Williams, A L, Ritter, Ann M, Stevens   +2 more
openaire   +2 more sources

Phytohormone-mediated interkingdom signaling shapes the outcome of rice-Xanthomonas oryzae pv. oryzae interactions [PDF]

, 2015
Background: Small-molecule hormones are well known to play key roles in the plant immune signaling network that is activated upon pathogen perception. In contrast, little is known about whether phytohormones also directly influence microbial virulence ...
De Vleesschauwer, David, He, Ya-Wen, Höfte, Monica, Kojima, Mikiko, Sakakibari, Hitoshi, Venturi, Vittorio, Xu, Jing, Zhou, Lian   +7 more
core   +2 more sources

Analysis of Activator and Repressor Functions Reveals the Requirements for Transcriptional Control by LuxR, the Master Regulator of Quorum Sensing in Vibrio harveyi

mBio, 2013
LuxR-type transcription factors are the master regulators of quorum sensing in vibrios. LuxR proteins are unique members of the TetR superfamily of transcription factors because they activate and repress large regulons of genes.
Julia C. van Kessel, Luke E. Ulrich, Igor B. Zhulin, Bonnie L. Bassler   +3 more
doaj   +1 more source

Genetic and functional characterization of the gene cluster directing the biosynthesis of putisolvin I and II in Pseudomonas putida strain PCL1445 [PDF]

, 2008
Pseudomonas putida PCL1445 secretes two cyclic lipopeptides, putisolvin I and putisolvin II, which possess a surface-tension-reducing ability, and are able to inhibit biofilm formation and to break down biofilms of Pseudomonas species including ...
Bloemberg, G.V., Coppoolse, E.R., Dubern, J.F., Stiekema, W.J.   +3 more
core   +2 more sources