Specificity of Signal-Binding via Non-AHL LuxR-Type Receptors. [PDF]
Quorum sensing is a typical communication system among Gram-negative bacteria used to control group-coordinated behavior via small diffusible molecules dependent on cell number.
Sophie Brameyer, Ralf Heermann
doaj +2 more sources
Conversion of the Vibrio fischeri Transcriptional Activator, LuxR, to a Repressor [PDF]
ABSTRACT The Vibrio fischeri luminescence ( lux ) operon is regulated by a quorum-sensing system that involves the transcriptional activator (LuxR) and an acyl-homoserine lactone signal. Transcriptional activation requires the presence of a 20-base inverted repeat termed the
K A, Egland, E P, Greenberg
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Bacterial LuxR solos have evolved to respond to different molecules including signals from plants [PDF]
A future challenge will be understanding the extensive communication that most likely takes place in bacterial interspecies and interkingdom signaling between plants and bacteria.
Hitendra K. Patel +5 more
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Effect of PAS-LuxR Family Regulators on the Secondary Metabolism of Streptomyces
With the development of sequencing technology and further scientific research, an increasing number of biosynthetic gene clusters associated with secondary Streptomyces metabolites have been identified and characterized.
Naifan Zhang +3 more
doaj +3 more sources
Microbes are a major source of antibiotics, pharmaceuticals, and other bioactive compounds. The production of many specialized microbial metabolites is encoded in biosynthetic gene clusters (BGCs). A challenge associated with natural product discovery is
Carolyn A. Brotherton +2 more
doaj +3 more sources
Functional Characterisation of the Quorum-Sensing Regulator ExpR<sub>Ecz</sub> in Modulation of Dickeya oryzae Motility and Virulence. [PDF]
In the absence of OHHL synthase ExpIEcz, ExpREcz represses self‐expression via EDDR region and regulates Dickeya oryzae virulence traits. OHHL synthesised via ExpIEcz abolishes ExpREcz function but promotes OHHL production and D. oryzae virulence.
Liang Z +8 more
europepmc +2 more sources
Intragenic suppression of a mutation: Characterization of an autoinducer-independent LuxR [PDF]
The Vibrio fischeri luminescence genes are activated by the LuxR protein and a diffusible signal termed the autoinducer. LuxR consists of two domains, a C-terminal transcriptional activator domain, and an N-terminal autoinducer-binding domain, which serves to regulate the function of the C-terminal domain.
K A, Poellinger +3 more
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Orphan LuxR regulators of quorum sensing [PDF]
Bacteria can modulate their behavior by releasing and responding to the accumulation of signal molecules. This population co-ordination, referred to as quorum sensing, is prevalent in Gram-negative and Gram-positive bacteria. The essential constituents of quorum-sensing systems include a signal producer, or synthase, and a cognate transcriptional ...
Arati V, Patankar, Juan E, González
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Microbial Primer: LuxR-LuxI Quorum Sensing.
Quorum sensing is a term describing bacterial cell-to-cell communication systems for monitoring and responding to changes in population density. This primer serves as an introduction to the canonical LuxR-LuxI-type quorum sensing circuits common to many species of Gram-negative bacteria.
Soto-Aceves, Martin P. +2 more
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LitR directly upregulates autoinducer synthesis and luminescence in Aliivibrio logei [PDF]
LitR is a master-regulator of transcription in the ainS/R and luxS/PQ quorum sensing (QS) systems of bacteria from Vibrio and Aliivibrio genera. Here, we for the first time directly investigated the influence of LitR on gene expression in the luxI/R QS ...
Sergey Bazhenov +7 more
doaj +2 more sources

