Results 151 to 160 of about 71,612 (209)

Holocene climate oscillations, seismotectonic events and human–environmental interactions reconstructed from the Giannades palaeolake on Corfu (Eastern Mediterranean, Greece)

Journal of Quaternary Science, EarlyView.
ABSTRACT The Mediterranean is particularly sensitive to rapid climate changes (RCCs) during the Holocene. An increasing number of natural climate archives revealed that socio‐economic developments were influenced by such RCCs since the Palaeolithic. However, multi‐millennial and high‐resolution archives are still rare and often located in mountainous ...
Esra Reichert, Peter Fischer, Bernd Zolitschka, Tina Georg, Lea Obrocki, Denis Scholz, Katja Sporn, Andreas Vött   +7 more
wiley   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

Usefulness of Gamma‐Glutamyl Transferase and Sequential Carbohydrate‐Deficient Transferrin for Unhealthy Alcohol Use Screening in Indigenous Communities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Unhealthy alcohol use (UAU) screening facilitates identification of patients with alcohol use problems for intervention. This study evaluates the usefulness of gamma‐glutamyl transferase (GGT) and sequential percentage of carbohydrate‐deficient transferrin (%CDT) in community screening for UAU.
Jing‐Houng Wang, Hui‐Min Tien, Hsiao‐Chu Lien, Pei‐Lin Chou, Yu‐Ling Chen, Nien‐Tzu Hsu, Sheng‐Nan Lu   +6 more
wiley   +1 more source

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang, Li Yang, Ling Wang, Xiao‐Qing Zhang, Jie Wang   +4 more
wiley   +1 more source

Posterior tibial slope increases over time in patients undergoing revision ACL reconstruction: A long‐term radiographic follow‐up study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Increased medial posterior tibial slope (PTS) is recognized as a significant risk factor for anterior cruciate ligament reconstruction (ACL‐R) failure. This study investigated radiographic changes in medial PTS over time among skeletally mature individuals undergoing revision ACL‐R and identified associated factors contributing to PTS ...
Mahmut Enes Kayaalp, Jumpei Inoue, Koji Nukuto, Joseph D Giusto, Gillian Ahrendt, Jonathan D. Hughes, James J. Irrgang, Thorkell Snæbjörnsson, Jon Karlsson, Volker Musahl   +9 more
wiley   +1 more source

Dynamic coronal plane knee alignment: Femoral anatomy determines kinematic curve morphology, tibial anatomy determines curve position

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose A single hip–knee–ankle angle (HKA) angle does not reflect the biomechanics of native, arthritic or prosthetic knees. Since HKA varies throughout flexion, dynamic coronal alignment is best represented by a kinematic curve plotting HKA against the range of motion.
Petros Ismailidis, Anthony Leicht, Kenji Doma, Peter McEwen   +3 more
wiley   +1 more source

Improved surgical accuracy in total knee arthroplasty using the ROSA® knee system: A randomised‐controlled unblinded trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic‐assisted total knee arthroplasty (RATKA) has been connected to improved surgical precision and implant alignment compared to conventional TKA (CTKA), with limited evidence from randomised‐controlled trials (RCT) and a large range of different systems on the market. Consequently, this study aimed to compare RATKA using the ROSA®
Alexander Möller, Feras Kasabji, Maximilian Fischer, Janosch Schoon, André Hofer, Georgi Iwan Wassilew, Johannes Christian Reichert   +6 more
wiley   +1 more source

Experience with arthroscopic treatment of disorders in the sternoclavicular joint: A prospective series of 78 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate pain, function and patient‐reported outcomes following arthroscopically intended treatment of painful sternoclavicular joint (SCJ) conditions between 2010 and 2024 in a consecutive cohort with long‐term follow‐up including 78 patients.
Anna Hoerby Normann Rasmussen, Martin Wyman Rathcke, Michael Rindom Krogsgaard   +2 more
wiley   +1 more source

Development of a National Laryngology Fellowship Curriculum: Standardizing Fellow Education

The Laryngoscope, EarlyView.
ABSTRACT Objectives To describe the development of the Laryngology Fellow Online Curriculum (LFOC) for fellowship education and review its impact on standardizing the educational experience for Laryngology fellows. Methods Surveys were completed from 2020 to 2024 by Laryngology fellows upon their fellowship graduation and completion of the LFOC ...
Brad W. deSilva
wiley   +1 more source

Longitudinal Analysis of Oral Potentially Malignant Disorder Conversion to Malignancy

The Laryngoscope, EarlyView.
ABSTRACT Objectives Oral potentially malignant disorders (OPMDs) are local and systemic conditions that can result in oral malignancies. We have had an OPMD surveillance program for 25 years covering over 30% of our state's population. More recent electronic health record search techniques have allowed us to analyze over 1500 patients in over a 10‐year
Benjamin Palatnik, Lindsey Mortensen, Aleksandr Palatnik, Beverly R. Wuertz, Frank G. Ondrey   +4 more
wiley   +1 more source