Results 211 to 220 of about 15,842 (278)

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia   +35 more
wiley   +1 more source

Fiscal Cyclicality and Debt Sustainability: Evidence From Over a Century of Data

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT Using a historical fiscal dataset for a group of 11 economies over the period 1880–2022, we examine debt sustainability and fiscal policy cyclicality and assess the factors influencing fiscal behaviour. We find that positive and statistically significant responses of primary balances to debt emerge in specific historical episodes and ...
Christos Chrysanthakopoulos   +2 more
wiley   +1 more source

Effectiveness of immersive virtual reality‐based interventions for alleviating peri‐ and post‐procedural pain and anxiety in gynecologic settings: A systematic review and meta‐analysis of randomized controlled trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Non‐pharmacological and complementary therapeutic, notably immersive virtual reality‐based interventions (IVR), could alleviate pain and anxiety associated with gynecologic procedures. Objective To evaluate the effectiveness of IVR in reducing peri‐ and post‐procedural pain and anxiety in gynecologic procedures.
Cristina González‐Lara   +4 more
wiley   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

open access: yesiLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang   +6 more
wiley   +1 more source

Fulminant neonatal listeriosis with death within 24 hours in a preterm infant: a case report. [PDF]

open access: yesBMC Infect Dis
Tao X   +7 more
europepmc   +1 more source

Evapotranspiration Estimation and Irrigation Performance Assessment Using Remote Sensing: A Case Study of the Ergani Dam Irrigation System (Turkey)

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Efficient water resource management is critical for sustainable agriculture, with evapotranspiration (ET) serving as a key parameter. Remote sensing (RS) techniques offer cost‐effective approaches for ET estimation and irrigation performance assessment in extensive agricultural systems.
Kivanç Hayri Doganay   +1 more
wiley   +1 more source

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