Results 121 to 130 of about 206,376 (396)

Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility

Advanced Science, EarlyView.
Cysteine attracts interest due to its unique electrochemical activity and emerging relationship with disulfidptosis. This study develops a new electrochemical nanosensor, which represents the first of its kind capable of detecting intracellular cysteine for various types of tumor cells and primary tumor cells in mice to evaluate disulfidptosis ...
Congcong Zhang, Xiangdi Zhang, Shushen Li, Yuyang Li, Bei Yuan, Mingshuang Zheng, Shuo Zhang, Fangping Yuan, Min Jia, Lixia Lu, Jun Zhou, Zhenguo Zhang, Xin Du   +12 more
wiley   +1 more source

Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]

, 2015
Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel, Migdal, Christopher, Schenk, Simon   +2 more
core   +2 more sources

Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6*

Journal of Biological Chemistry, 2017
Alginate lyases that degrade alginate via a β-elimination reaction fall into seven polysaccharide lyase (PL) families. Although the structures and catalytic mechanisms of alginate lyases in the other PL families have been clarified, those in family PL6 ...
Fei Xu, F. Dong, Peng Wang, H. Cao, Chunyang Li, Ping-Yi Li, Xiuhua Pang, Yu-Zhong Zhang, Xiulan Chen   +8 more
semanticscholar   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Import of cytochrome c into mitochondria [PDF]

, 1989
The covalent attachment of heme to apocytochrome c, and therefore the import of cytochrome c into mitochondria, is dependent on both NADH plus a cytosolic cofactor that has been identified to be FMN or FAD.
Neupert, Walter, Nicholson, Donald W.
core  

Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02

Marine Drugs, 2018
Alginate lyases are enzymes that degrade alginate into oligosaccharides which possess a variety of biological activities. Discovering and characterizing novel alginate lyases has great significance for industrial and medical applications.
Jingjing Zhuang, Keke Zhang, Xiaohua Liu, Weizhi Liu, Qianqian Lyu, A. Ji   +5 more
semanticscholar   +1 more source

Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. [PDF]

, 1983
We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform different immunologic functions.
Cantor, H, der Simonian, H, Dvorak, AM, Dvorak, HF, Galli, SJ, Goldin, J, Marcum, JA, Monahan, RA, Nabel, G, Pyne, K, Rosenberg, RD   +10 more
core  

Nanogram amounts of salicylic acid produced by the rhizobacterium Pseudomonas aeruginosa 7NSK2 activate the systemic acquired resistance pathway in bean [PDF]

, 1999
Root colonization by specific nonpathogenic bacteria can induce a systemic resistance in plants to pathogen infections. In bean, this kind of systemic resistance can be induced by the rhizobacterium Pseudomonas aeruginosa 7NSK2 and depends on the ...
Audenaert, Kris, Buchala, Antony, Capiau, Kristof, De Meyer, Geert, Höfte, Monica, Métraux, Jean-Pierre   +5 more
core   +2 more sources

Biochemical characterization of a novel ulvan lyase from Pseudoalteromonas sp. strain PLSV

RSC Advances, 2018
Ulvans, complex polysaccharides found in the ulvales (green seaweed) cell wall, contain predominantly 3-sulfated rhamnose (Rha3S) linked to either d-glucuronic acid, l-iduronic acid or d-xylose.
H. Qin, Panpan Xu, Q. Guo, Xiaotao Cheng, D. Gao, Dengyue Sun, Zhangliang Zhu, F. Lu   +7 more
semanticscholar   +1 more source

Molecular identification of hyaluronate lyase, not hyaluronidase, as an intrinsic hyaluronan-degrading enzyme in Clostridium perfringens strain ATCC 13124

Scientific Reports
Clostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor.
Tomoya Kumon, Sayoko Oiki, Wataru Hashimoto   +2 more
doaj   +1 more source