Results 121 to 130 of about 197,995 (383)

Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface

open access: yesAdvanced Science, EarlyView.
Drop‐on‐demand printing is used to replicate the spatial compartmentalization of the breast cancer‐host interface. Hydrogel confinement affects phenotypic changes in cells at the spheroid interface that drives a two‐fold increase in chemotherapeutic resistance compared to control unconfined spheroids.
Bram G. Soliman   +4 more
wiley   +1 more source

Abnormally high content of free glucosamine residues identified in a preparation of commercially available porcine intestinal heparan sulfate [PDF]

open access: yes, 2016
Heparan sulfate (HS) polysaccharides are ubiquitous in animal tissues as components of proteoglycans, and they participate in many important biological processes.
Chai, W   +8 more
core   +1 more source

A novel ulvan lyase family with broad-spectrum activity from the ulvan utilisation loci of Formosa agariphila KMM 3901

open access: yesScientific Reports, 2018
Ulvan, which is one of the major structural polysaccharides of the cell walls of green macroalgae, is degraded by ulvan lyases via the β-elimination mechanism with the release of oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4 ...
Venkat Rao Konasani   +3 more
semanticscholar   +1 more source

How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]

open access: yes, 2017
Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias   +2 more
core   +2 more sources

Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02

open access: yesMarine Drugs, 2018
Alginate lyases are enzymes that degrade alginate into oligosaccharides which possess a variety of biological activities. Discovering and characterizing novel alginate lyases has great significance for industrial and medical applications.
Jingjing Zhuang   +5 more
semanticscholar   +1 more source

Molecular identification of hyaluronate lyase, not hyaluronidase, as an intrinsic hyaluronan-degrading enzyme in Clostridium perfringens strain ATCC 13124

open access: yesScientific Reports
Clostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor.
Tomoya Kumon   +2 more
doaj   +1 more source

Early steps in mitochondrial protein import [PDF]

open access: yes, 1990
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Neupert, Walter   +2 more
core   +1 more source

Import of cytochrome c into mitochondria [PDF]

open access: yes, 1989
The covalent attachment of heme to apocytochrome c, and therefore the import of cytochrome c into mitochondria, is dependent on both NADH plus a cytosolic cofactor that has been identified to be FMN or FAD.
Neupert, Walter, Nicholson, Donald W.
core  

Pay32p of the Yeast Yarrowia lipolytica Is an Intraperoxisomal Component of the Matrix Protein Translocation Machinery [PDF]

open access: yes, 1995
Pay mutants of the yeast Yarrowia lipolytica fail to assemble functional peroxisomes. One mutant strain, pay32-1, has abnormally small peroxisomes that are often found in clusters surrounded by membranous material.
Rachubinski, Richard A.,   +3 more
core   +3 more sources

Biochemical characterization of a novel ulvan lyase from Pseudoalteromonas sp. strain PLSV

open access: yesRSC Advances, 2018
Ulvans, complex polysaccharides found in the ulvales (green seaweed) cell wall, contain predominantly 3-sulfated rhamnose (Rha3S) linked to either d-glucuronic acid, l-iduronic acid or d-xylose.
H. Qin   +7 more
semanticscholar   +1 more source

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