Results 131 to 140 of about 169,030 (353)

Lactylation in cancer biology: Unlocking new avenues for research and therapy

open access: yesCancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou   +6 more
wiley   +1 more source

Selective Oxidation of α,β‐Unsaturated Alcohols With Lyophilisates of Bjerkandera adusta

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The biocatalytic aerobic production of (E)‐2‐allylic aldehydes from their corresponding alcohols using lyophilisates of the basidiomycetous fungus Bjerkandera adusta is reported. The addition of small amounts of organic solvents to the reaction media increased the reaction and substrate conversion rates, allowing for to produce (E)‐aldehydes ...
Letizia Calza   +4 more
wiley   +1 more source

Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A.

open access: yesPLoS ONE, 2014
Alginate is a polysaccharide produced by certain seaweeds and bacteria that consists of mannuronic acid and guluronic acid residues. Seaweed alginate is used in food and industrial chemical processes, while the biosynthesis of bacterial alginate is ...
Steven M Swift   +4 more
doaj   +1 more source

Integrated In Vitro and In Silico Characterization of 5‐Hydroxyferulic Acid: Antioxidant, Anti‐Inflammatory, Anti‐Hemolytic, and Cytotoxic Potential

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT In the pursuit of novel antioxidant and anti‐inflammatory agents, we investigated 5‐hydroxyferulic acid (5‐OHFA), a hydroxylated derivative of the well‐known phenolic compound ferulic acid (FA). This study aimed to determine whether structural modification enhances the biological activity of FA.
Syrine Sakouhi   +5 more
wiley   +1 more source

5‐Thiohistidine N‐Acetyltransferase from Proteiniphilum Saccharofermentans

open access: yesChemBioChem, EarlyView.
Proteiniphilum saccharofermentans, a Gram‐negative facultative anaerobe, produces an N‐acetyl transferase (5THNAT) that acetylates 5‐thiohistidine using acetyl‐CoA. This reaction competes with OvoC‐mediated Nπ‐methylation of the same substrate.
Cangsong Liao   +3 more
wiley   +1 more source

Ultrafiltration Fibers like Bioreactors [PDF]

open access: yes, 2001
A polysulfone ultrafiltration membrane with pectinase physically immobilized on it by a dynamic formation method was used to examine the potential of these reactive membranes in applications involving solutions containing pectin.
Carrin, Maria Elena   +2 more
core  

In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins

open access: yesChemBioChem, EarlyView.
This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies   +2 more
wiley   +1 more source

SiO2–alginate–melittin nano-conjugates suppress the proliferation of ovarian cancer cells: a controlled release approach leveraging alginate lyase

open access: yesCancer Nanotechnology
Background Ovarian cancer treatment is challenged by resistance and off-target effects. Melittin shows promise against cancer but is limited by its instability and harmful cellular interactions. Our study introduces SiO2–alginate–melittin nano-conjugates
Lihui Si   +5 more
doaj   +1 more source

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