Results 31 to 40 of about 94,605 (314)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Estradiol of various saturation and its influence on hydrogen sulfide formation in the myocardium of female rats. [PDF]
Medičnì Perspektivi, 2015 Hydrogen sulfide is signalling molecule that regulates vascular tone and myocardial contractility. Role of estradiol in hydrogen sulfide production in cardiovascular system of rats remains unclear and this becames research objective.
A. V. Melnik
doaj +2 more sources
Scientific Reports, 2021 While most restriction enzymes catalyze the hydrolysis of phosphodiester bonds at specific nucleotide sequences in DNA, restriction enzymes of the HALFPIPE superfamily cleave N-glycosidic bonds, similar to DNA glycosylases.
Ken-ichi Miyazono +3 more
doaj +1 more source
Microplastics from Wearable Bioelectronic Devices: Sources, Risks, and Sustainable Solutions
Advanced Functional Materials, EarlyView.Bioelectronic devices (e.g., e‐skins) heavily rely on polymers that at the end of their life cycle will generate microplastics. For research, a holistic approach to viewing the full impact of such devices cannot be overlooked. The potential for devices as sources for microplastics is raised, with mitigation strategies surrounding polysaccharide and ...
Conor S. Boland
wiley +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, EarlyView.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Acta Dermato-VenereologicaATP citrate lyase, the first rate-limiting enzyme in de novo lipogenesis, plays a crucial role in tumour progression. This study explores ATP citrate lyase’s potential as a tumour biomarker and its role in cutaneous squamous cell carcinoma.
Ruiting Luo +6 more
doaj +1 more source
Alginate Lyase of a Novel Algae Fermentation Strain [PDF]
Chemical and Biochemical Engineering Quarterly, 2019 A novel algae fermentation strain was obtained in our previous work. This strain can produce alginate lyase and alcohol dehydrogenase used for the ethanol fermentation from algae.
W. Zhang, X. Xia, Z. Zhang
doaj +1 more source
Advanced Materials, EarlyView.Microarchitecture sculpting via phase separation programs hydrogel mechanics by creating globular, inverse globular, and spinodal structures. Spinodal architectures deliver superior toughness and energy dissipation, while ionic modulation through single polymer phase separation offers a simple, scalable route to tune mechanical properties ...
Castro Johnbosco +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 目的探讨S1P lyase在肝癌中的表达情况,及其对肝癌预后的影响。方法选取桂林医学院附属医院54例肝细胞癌患者,real-time PCR分析S1P lyase在54对肝细胞癌癌组织及癌旁组织中的表达,运用统计学方法探讨S1P lyase表达与肝癌临床病理特征的关系;利用Kaplan-Meier分析S1P lyase对肝癌预后的影响;应用STRING数据库初步探讨神经鞘脂信号通路中可能与S1P lyase相互作用的信号分子。结果 S1P lyase在肝癌组织中的表达明显低于癌旁组织 ...
邱志东 +3 more
doaj
Screening of alginate lyase-excreting microorganisms from the surface of brown algae
AMB Express, 2017 Alginate lyase is a biocatalyst that degrades alginate to produce oligosaccharides, which have many bioactive functions and could be used as renewable biofuels.
Mingpeng Wang +5 more
doaj +1 more source