Structural and functional insights into Uly1040, an ulvan lyase from polysaccharide lyase family 40 [PDF]
Applied and Environmental MicrobiologyUlvan is a major polysaccharide in marine green algae. Its oligosaccharide degradation products possess diverse bioactivities and hold considerable potential for various applications.
Hou-Qi Wang +9 more
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Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum [PDF]
eLifeRecently, a new class of glycosaminoglycan (GAG) lyases (GAGases) belonging to PL35 family has been discovered with an ultrabroad substrate spectrum that can degrade three types of uronic acid-containing GAGs (hyaluronic acid, chondroitin sulfate and ...
Lin Wei +11 more
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Hidden Activities of Tyrosine Phenol-Lyase and Tryptophan Indole-Lyase: Recombinant PLP-Dependent C–C Lyases as New Biocatalysts for Antimicrobial Thiosulfinate Generation [PDF]
PharmaceuticalsBackground: Lyases are used in a wide scope of applications, making them invaluable tools in both industrial biotechnology and molecular biology. Many examples of lyases belong to the extensive family of pyridoxal 5′-phosphate (PLP)-dependent enzymes ...
Vitalia V. Kulikova +6 more
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Biochemical, Kinetic, and Spectroscopic Characterization of Ruegeria pomeroyi DddW--A Mononuclear Iron-Dependent DMSP Lyase. [PDF]
PLoS ONE, 2015 The osmolyte dimethylsulfoniopropionate (DMSP) is a key nutrient in marine environments and its catabolism by bacteria through enzymes known as DMSP lyases generates dimethylsulfide (DMS), a gas of importance in climate regulation, the sulfur cycle, and ...
Adam E Brummett +4 more
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A twin xanthan lyase-dependent xanthan degradation system in Paenibacillus taichungensis I5 [PDF]
Applied Microbiology and BiotechnologyXanthan gum, a natural heteropolysaccharide produced by Xanthomonas species, has many biotechnological applications across industries due to its unique rheological properties.
Rui Han +6 more
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A comparative study of the efficacy of alginate lyases in the presence of metal ions elevated in the cystic fibrosis lung milieu [PDF]
Biochemistry and Biophysics ReportsPseudomonas aeruginosa, a common cause of morbidity in cystic fibrosis, chronically infects the patient's lungs by forming an alginate-containing biofilm.
Neetu, T.N.C. Ramya
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Recent Advances in Alginate Lyase Engineering for Efficient Conversion of Alginate to Value‐Added Products [PDF]
Microbial BiotechnologyAlginate lyases depolymerize alginate and generate alginate oligosaccharides (AOS) and eventually 4‐deoxy‐L‐erythro‐5‐hexoseulose uronate (DEH), a monosaccharide.
Hyo Jeong Shin +5 more
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Insights into the mechanism of substrate specificity in a novel PL15_3 subfamily oligo-alginate lyase VBAly15A [PDF]
Applied and Environmental MicrobiologyAlginate is a major component of brown algae cell walls and can be degraded via β-elimination by alginate lyases. These enzymes are classified into polysaccharide lyases and oligo-alginate lyases (Oals), with Oals mainly represented by the PL15 and PL17 ...
Yongqi Tang +4 more
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Alginate Lyases from Marine Bacteria: An Enzyme Ocean for Sustainable Future
Molecules, 2022 The cell wall of brown algae contains alginate as a major constituent. This anionic polymer is a composite of β-d-mannuronate (M) and α-l-guluronate (G).
Noora Barzkar +6 more
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Marine Drugs, 2022 Alginate oligosaccharides (AOS) have many biological activities and significant applications in prebiotics, nutritional supplements, and plant growth development. Alginate lyases have unique advantages in the preparation of AOS.
Zhao Xue +7 more
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