Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum [PDF]
eLifeRecently, a new class of glycosaminoglycan (GAG) lyases (GAGases) belonging to PL35 family has been discovered with an ultrabroad substrate spectrum that can degrade three types of uronic acid-containing GAGs (hyaluronic acid, chondroitin sulfate and ...
Lin Wei +11 more
doaj +2 more sources
A twin xanthan lyase-dependent xanthan degradation system in Paenibacillus taichungensis I5 [PDF]
Applied Microbiology and BiotechnologyXanthan gum, a natural heteropolysaccharide produced by Xanthomonas species, has many biotechnological applications across industries due to its unique rheological properties.
Rui Han +6 more
doaj +2 more sources
A comparative study of the efficacy of alginate lyases in the presence of metal ions elevated in the cystic fibrosis lung milieu [PDF]
Biochemistry and Biophysics ReportsPseudomonas aeruginosa, a common cause of morbidity in cystic fibrosis, chronically infects the patient's lungs by forming an alginate-containing biofilm.
Neetu, T.N.C. Ramya
doaj +2 more sources
Insights into the mechanism of substrate specificity in a novel PL15_3 subfamily oligo-alginate lyase VBAly15A [PDF]
Applied and Environmental MicrobiologyAlginate is a major component of brown algae cell walls and can be degraded via β-elimination by alginate lyases. These enzymes are classified into polysaccharide lyases and oligo-alginate lyases (Oals), with Oals mainly represented by the PL15 and PL17 ...
Yongqi Tang +4 more
doaj +2 more sources
Recent Advances in Alginate Lyase Engineering for Efficient Conversion of Alginate to Value‐Added Products [PDF]
Microbial BiotechnologyAlginate lyases depolymerize alginate and generate alginate oligosaccharides (AOS) and eventually 4‐deoxy‐L‐erythro‐5‐hexoseulose uronate (DEH), a monosaccharide.
Hyo Jeong Shin +5 more
doaj +2 more sources
Alginate Lyases from Marine Bacteria: An Enzyme Ocean for Sustainable Future
Molecules, 2022 The cell wall of brown algae contains alginate as a major constituent. This anionic polymer is a composite of β-d-mannuronate (M) and α-l-guluronate (G).
Noora Barzkar +6 more
doaj +1 more source
Marine Drugs, 2022 Alginate oligosaccharides (AOS) have many biological activities and significant applications in prebiotics, nutritional supplements, and plant growth development. Alginate lyases have unique advantages in the preparation of AOS.
Zhao Xue +7 more
doaj +1 more source
Journal of Fungi, 2021 Alginate is an anionic polysaccharide abundantly present in the cell walls of brown macroalgae. The enzymatic depolymerization is performed solely by alginate lyases (EC 4.2.2.x), categorized as polysaccharide lyases (PLs) belonging to 12 different PL ...
Bo Pilgaard +4 more
doaj +1 more source
Genes for degradation and utilization of uronic acid-containing polysaccharides of a marine bacterium Catenovulum sp. CCB-QB4 [PDF]
PeerJ, 2021 Background Oligosaccharides from polysaccharides containing uronic acids are known to have many useful bioactivities. Thus, polysaccharide lyases (PLs) and glycoside hydrolases (GHs) involved in producing the oligosaccharides have attracted interest in ...
Go Furusawa +2 more
doaj +2 more sources
Functional Exploration of the Polysaccharide Lyase Family PL6. [PDF]
PLoS ONE, 2016 Alginate, the main cell-wall polysaccharide of brown algae, is composed of two residues: mannuronic acid (M-residues) and, its C5-epimer, guluronic acid (G-residues).
Sophie Mathieu +4 more
doaj +1 more source