Results 131 to 140 of about 29,495 (296)

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

The gut microbiome in atherosclerotic cardiovascular disease [PDF]

, 2017
et al,, Peng, Yangqing
core   +2 more sources

Regulation of the \u3cem\u3eEscherichia coli\u3c/em\u3e Tryptophan Operon by Early Reactions in the Aromatic Pathway [PDF]

, 1970
7-Methyltryptophan (7MT) or compounds which can be metabolized to 7MT, 3-methylanthranilic acid (3MA) and 7-methylindole, cause derepression of the trp operon through feedback inhibition of anthranilate synthetase. Tyrosine reverses 3MA or 7-methylindole
Held, William A., Smith, Oliver H.
core   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Unraveling the molecular mechanism of polysaccharide lyases for efficient alginate degradation

Nature Communications
Alginate lyases (ALs) catalyze the depolymerization of brown macroalgae alginates, widely used naturally occurring polysaccharides. Their molecular reaction mechanism remains elusive due to the lack of catalytically competent Michaelis-Menten-like ...
José Pablo Rivas-Fernández, Marlene Vuillemin, Bo Pilgaard, Leesa J. Klau, Folmer Fredslund, Charlotte Lund-Hanssen, Ditte H. Welner, Anne S. Meyer, J. Preben Morth, Flora Meilleur, Finn L. Aachmann, Carme Rovira, Casper Wilkens   +12 more
doaj   +1 more source

Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects

Pest Management Science, EarlyView.
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz, Yure Marin Guidi, Mariana Ramirez‐Castillo, Fernando Storniolo Adegas, Caio Antonio Carbonari, Edivaldo Domingues Velini, Rafael De Prado, Stephen O. Duke   +7 more
wiley   +1 more source

The Mechanisms of Chondroitin Sulphate Lyases Treatment in Promotion of Axonal Growth [PDF]

, 2012
Poster PresentationIn Injured nerves, chondroitin sulphate (CS) is upregulated forming barriers with astrocytes/fibroblasts and other extracellular matrix molecules, and thereby hampering nerve regeneration.
Chan, YS, Shum, DKY, Tam, KW
core  

RNA interference in crop protection: opportunities and challenges during the transition to commercialization

Pest Management Science, EarlyView.
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi, Anna Narduzzo, Alessandra Di Canito, Francesco Favaretto, Luca Nerva, Walter Chitarra, Lucia Bologna, Jacopo Bacenetti, Giuliana Maddalena, Simona Masiero, Ileana Vigentini, Gabriella De Lorenzis, Silvia Laura Toffolatti   +12 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Hydroxynitrile Lyases: Biological Sources and Application as Biocatalysts

Food Technology and Biotechnology, 2004
We review the state of the art regarding the application of hydroxynitrile lyases to obtain, enantioselectively, (R)- and (S)-cyanohydrins of aldehydes and ketones.
Herfried Griengl, Martin H. Fechter
doaj