Results 1 to 10 of about 3,768 (92)

A Recombinant Alginate Lyase Algt1 with Potential in Preparing Alginate Oligosaccharides at High-Concentration Substrate. [PDF]

Foods, 2023
Alginate lyase has been demonstrated as an efficient tool in the preparation of functional oligosaccharides (AOS) from alginate. The high viscosity resulting from the high concentration of alginate poses a limiting factor affecting enzymatic hydrolysis, particularly in the preparation of the fragments with low degrees of polymerization (DP).
Liang Q, Huang Y, Liu Z, Xiao M, Ren X, Liu T, Li H, Yu D, Wang Y, Zhu C.   +9 more
europepmc   +4 more sources

A Novel Cold-Adapted and High-Alkaline Alginate Lyase with Potential for Alginate Oligosaccharides Preparation. [PDF]

Molecules, 2023
Alginate oligosaccharides (AOs) prepared through enzymatic reaction by diverse alginate lyases under relatively controllable and moderate conditions possess versatile biological activities. But widely used commercial alginate lyases are still rather rare due to their poor properties (e.g., lower activity, worse thermostability, ion tolerance, etc.). In
Wang HY, Chen ZF, Zheng ZH, Lei HW, Cong HH, Zhou HX.   +5 more
europepmc   +4 more sources

Advances in Research on the Bioactivity of Alginate Oligosaccharides. [PDF]

Mar Drugs, 2020
Alginate is a natural polysaccharide present in various marine brown seaweeds. Alginate oligosaccharide (AOS) is a degradation product of alginate, which has received increasing attention due to its low molecular weight and promising biological activity. The wide-ranging biological activity of AOS is closely related to the diversity of their structures.
Xing M, Cao Q, Wang Y, Xiao H, Zhao J, Zhang Q, Ji A, Song S.   +7 more
europepmc   +5 more sources

Expression, Purification, and Characterisation of Recombinant Alginate Lyase (Flammeovirga AL2) for the Bioconversion of Alginate into Alginate Oligosaccharides. [PDF]

Molecules
Alginate, a polysaccharide found in brown seaweeds, has regularly gained attention for its potential use as a source of bioactive compounds. However, it is structurally complex with a high molecular weight, limiting its application. Alginate oligosaccharides (AOS) are small, soluble fragments, making them more bioavailable.
Grobler CE, Mabate B, Prins A, Le Roes-Hill M, Pletschke BI.   +4 more
europepmc   +4 more sources

Efficient Degradation of Alginate and Preparation of Alginate Oligosaccharides by a Novel Biofunctional Alginate Lyase with High Activity and Excellent Thermophilic Features. [PDF]

Mar Drugs, 2023
The enzymatic degradation of seaweed polysaccharides is gaining interest for its potential in the production of functional oligosaccharides and fermentable sugars. Herein, a novel alginate lyase, AlyRm3, was cloned from a marine strain, Rhodothermus marinus DSM 4252.
Li L, Cao S, Zhu B, Yao Z, Zhu B, Qin Y, Jiang J.   +6 more
europepmc   +4 more sources

Alginate Oligosaccharides Affect Mechanical Properties and Antifungal Activity of Alginate Buccal Films with Posaconazole. [PDF]

Mar Drugs, 2019
Sodium alginate and its oligosaccharides through potential antifungal properties might improve the activity of antifungal drugs enhancing their efficacy and potentially reducing the frequency of application. Mucoadhesive buccal films are oral dosage forms designed for maintaining both local or systemic drug effects and seem to be a very promising ...
Szekalska M, Wróblewska M, Trofimiuk M, Basa A, Winnicka K.   +4 more
europepmc   +5 more sources

Detection of Alginate Oligosaccharides from Mollusks [PDF]

Bioscience, Biotechnology, and Biochemistry, 2006
We attempted in this study to detect alginate oligosaccharides (AO) from mollusks. The samples used were digestive organs taken from turban shells and abalones which commonly ate brown algae. High-performance liquid chromatography (HPLC) and negative-ion electrospray ionization (ESI) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) analyses ...
CHAKI, Takamitsu, KAKIMI, Hideto, SHIBATA, Akihiro, BABA, Takashi   +3 more
openaire   +2 more sources

Potential applications of alginate oligosaccharides for biomedicine – A mini review

Carbohydrate Polymers, 2021
Extensive research on marine algae, especially on their health-promoting properties, has been conducted. Various ingredients with potential biomedical applications have been discovered and extracted from marine algae. Alginate oligosaccharides are low molecular weight alginate polysaccharides present in cell walls of brown algae.
Mingpeng, Wang, Lei, Chen, Zhaojie, Zhang   +2 more
openaire   +2 more sources

Metabolism and Calcium Antagonism of Sodium Alginate Oligosaccharides

Bioscience, Biotechnology, and Biochemistry, 2007
Sodium alginate oligosaccharides (NaAOs) consisting of a mixture of eight oligosaccharides have previously been reported to lower blood pressure. We investigated in this study the excretion of NaAOs into the urine or feces, and attempted to elucidate the mechanism for lowering blood pressure by using isolated mesenteric arteries from the rabbit.
CHAKI, Takamitsu, KAJIMOTO, Noriyoshi, OGAWA, Hiroshi, BABA, Takashi, HIURA, Nozomi   +4 more
openaire   +2 more sources

Imunomodulator Activity of Alginate Oligosaccharides from Alginate Sargassum crassifolium

Jurnal Pengolahan Hasil Perikanan Indonesia, 2017
Alginate oligosaccharides (AOS) are oligosaccharides produced from depolimerization of the alginate polymer, and is reported to have various biological activities. The study aims is to determine the effect of AOS<br />production conditions and their effects on products and its activities as an immunomodulatory compound.
Subaryono Subaryono, Rosmawati Perangiangin, Maggy Thenawidjaja Suhartono, Fransiska Rungkat Zakaria   +3 more
openaire   +2 more sources