Identification and Characterization of a New Cold-Adapted and Alkaline Alginate Lyase TsAly7A from Thalassomonas sp. LD5 Produces Alginate Oligosaccharides with High Degree of Polymerization [PDF]
Marine Drugs, 2022 Alginate oligosaccharides (AOS) and their derivatives become popular due to their favorable biological activity, and the key to producing functional AOS is to find efficient alginate lyases.
Chengying Yin +4 more
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Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms. [PDF]
Front Cell Infect Microbiol, 2023 BackgroundThe increasing prevalence of invasive fungal infections in immuno-compromised patients is a considerable cause of morbidity and mortality. With the rapid emergence of antifungal resistance and an inadequate pipeline of new therapies, novel treatment strategies are now urgently required.MethodsThe antifungal activity of the alginate ...
Powell LC +12 more
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Review on Preparation, Separation and Characterization of Alginate Oligosaccharide
Shipin gongye ke-ji, 2022 Alginate oligosaccharide (AOS) is a kind of low molecular polymer, which is composed of 2~25 monosaccharides (mannuronic acidandguluronic acid) by glycoside bond.
Yiqing LIU +6 more
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Elucidation of degrading pattern and substrate recognition of a novel bifunctional alginate lyase from Flammeovirga sp. NJ-04 and its use for preparation alginate oligosaccharides [PDF]
Biotechnology for Biofuels, 2019 Background The alginate oligosaccharides have been widely used in agriculture, medicine, and food industries due to their versatile physiological functions such as antioxidant, anticoagulant, and antineoplastic activities.
Benwei Zhu +4 more
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Genome Analysis of a Potential Novel Vibrio Species Secreting pH- and Thermo-Stable Alginate Lyase and Its Application in Producing Alginate Oligosaccharides [PDF]
Marine DrugsAlginate lyase is an attractive biocatalyst that can specifically degrade alginate to produce oligosaccharides, showing great potential for industrial and medicinal applications.
Ke Bao +4 more
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Effects of two kinds of marine algae polysaccharides and their oligosaccharides on lipid metabolism and gut microbiota in high-fat diet mice [PDF]
Microbiology SpectrumAbnormal lipid metabolism is manifested in a variety of metabolic diseases. In recent years, studies have shown that the pathogenesis of these disorders is closely associated with the gut microbiota.
Zi-ang Yao, Ling Xu, Yu Liu, Hai-ge Wu
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Synthesis of Alginate Oligosaccharide (AOS) Using Different Solvents [PDF]
Indonesian Journal of Biotechnology and Biodiversity, 2021 Alginate oligosaccharide (AOS) is an oligosaccharide synthesized by depolymerizing alginate and has various industrial applications. This research determines the best solvent and the optimal concentration of the best solvent to produce AOS. Peroxides and hydrochloric acid can be used[L1] as solvents, but the residue might cause some danger if the AOS ...
Nathaniel Nainggolan +2 more
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Detection of Alginate Oligosaccharides from Mollusks [PDF]
Bioscience, Biotechnology, and Biochemistry, 2006 We attempted in this study to detect alginate oligosaccharides (AO) from mollusks. The samples used were digestive organs taken from turban shells and abalones which commonly ate brown algae. High-performance liquid chromatography (HPLC) and negative-ion electrospray ionization (ESI) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) analyses ...
Takamitsu, Chaki +3 more
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Marine Drugs, 2023 Alginate oligosaccharides prepared by alginate lyases attracted great attention because of their desirable biological activities. However, the hydrolysis products are always a mixture of oligosaccharides with different degrees of polymerization, which ...
Zhiqiang Shu +7 more
doaj +1 more source
Expression and Characterization of an Alginate Lyase and Its Thermostable Mutant in Pichia pastoris
Marine Drugs, 2020 Alginate is one of the most abundant polysaccharides in algae. Alginate lyase degrades alginate through a β-elimination mechanism to produce alginate oligosaccharides with special bioactivities. Improving enzyme activity and thermal stability can promote
Suxiao Yang +6 more
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