Results 1 to 10 of about 262,571 (196)
Unraveling the molecular mechanism of polysaccharide lyases for efficient alginate degradation [PDF]
Nature CommunicationsAlginate lyases (ALs) catalyze the depolymerization of brown macroalgae alginates, widely used naturally occurring polysaccharides. Their molecular reaction mechanism remains elusive due to the lack of catalytically competent Michaelis-Menten-like ...
José Pablo Rivas-Fernández +12 more
doaj +9 more sources
FEMS Microbiology Reviews, 1995 Polysaccharide lyases are the products of various microorganisms, bacteriophage and some eukaryotes. All such enzymes cleave a hexose-1,4-alpha- or beta-uronic acid sequence by beta-elimination. They are in some examples, the only known type of enzymes degrading their polyanionic substrates.
I W Sutherland
exaly +6 more sources
A hierarchical classification of polysaccharide lyases for glycogenomics [PDF]
Biochemical Journal, 2010 Carbohydrate-active enzymes face huge substrate diversity in a highly selective manner using only a limited number of available folds. They are therefore subjected to multiple divergent and convergent evolutionary events. This and their frequent modularity render their functional annotation in genomes difficult in a number of cases.
Vincent Lombard +2 more
exaly +6 more sources
An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins. [PDF]
J Biol Chem, 2017 The human gut microbiota utilizes complex carbohydrates as major nutrients. The requirement for efficient glycan degrading systems exerts a major selection pressure on this microbial community.
Munoz-Munoz J +5 more
europepmc +7 more sources
Gellan lyases-novel polysaccharide lyases [PDF]
Microbiology (United Kingdom), 1994 A number of bacterial strains capable of degrading the bacterial exopolysaccharide gellan have been isolated by standard enrichment procedures. They include several pink-pigmented Gram-negative rod-shaped bacteria. A red-pigmented Gram-positive bacillus earlier found to degrade the exopolysaccharide xanthan from Xanthomonas campestris also showed ...
I W Sutherland
exaly +4 more sources
Polysaccharide lyases from gellan-producing Sphingomonas spp. [PDF]
Microbiology (United Kingdom), 1996 A number ofSphingomonasstrains capable of synthesizing the bacterial exopolysaccharide gellan and related polymers were shown to possess constitutive gellanase activity. In each case, the degradation of deacylated gellan was due to extracellular, eliminase-type enzymes (lyases) which cleave the sequence …ß-D-glucosyl 1,4-ß-D-glucuronosyl… in the ...
I W Sutherland
exaly +4 more sources
Structural and functional insights into Uly1040, an ulvan lyase from polysaccharide lyase family 40 [PDF]
Applied and Environmental MicrobiologyUlvan is a major polysaccharide in marine green algae. Its oligosaccharide degradation products possess diverse bioactivities and hold considerable potential for various applications.
Hou-Qi Wang +9 more
doaj +4 more sources
A new family of β-helix proteins with similarities to the polysaccharide lyases
Acta Crystallographica Section D: Biological Crystallography, 2014 Microorganisms that degrade biomass produce diverse assortments of carbohydrate-active enzymes and binding modules. Despite tremendous advances in the genomic sequencing of these organisms, many genes do not have an ascribed function owing to low sequence identity to genes that have been annotated.
Devin W Close +2 more
exaly +5 more sources
Recalcitrant cell wall of Ulva lactuca seaweed is degraded by a single ulvan lyase from family 25 of polysaccharide lyases. [PDF]
Anim Nutr, 2022 Green macroalgae, e.g., Ulva lactuca, are valuable bioactive sources of nutrients; but algae recalcitrant cell walls, composed of a complex cross-linked matrix of polysaccharides, can compromise their utilization as feedstuffs for monogastric animals ...
Costa MM +9 more
europepmc +2 more sources
Structural Determinants Responsible for Substrate Recognition and Mode of Action in Family 11 Polysaccharide Lyases [PDF]
Journal of Biological Chemistry, 2009 A saprophytic Bacillus subtilis secretes two types of rhamnogalacturonan (RG) lyases, endotype YesW and exotype YesX, which are responsible for an initial cleavage of the RG type I (RG-I) region of plant cell wall pectin.
Akihito Ochiai +2 more
exaly +4 more sources