Unraveling the molecular mechanism of polysaccharide lyases for efficient alginate degradation [PDF]
Nature CommunicationsAlginate lyases (ALs) catalyze the depolymerization of brown macroalgae alginates, widely used naturally occurring polysaccharides. Their molecular reaction mechanism remains elusive due to the lack of catalytically competent Michaelis-Menten-like ...
Marlène Vuillemin +2 more
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Functional Exploration of the Polysaccharide Lyase Family PL6 [PDF]
PLoS ONE, 2016 Alginate, the main cell-wall polysaccharide of brown algae, is composed of two residues: mannuronic acid (M-residues) and, its C5-epimer, guluronic acid (G-residues).
Bernard Henrissat
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FEMS Microbiology Reviews, 1995 Polysaccharide lyases are the products of various microorganisms, bacteriophage and some eukaryotes. All such enzymes cleave a hexose-1,4-alpha- or beta-uronic acid sequence by beta-elimination. They are in some examples, the only known type of enzymes degrading their polyanionic substrates.
Kennedy, Lynn
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Structural and functional insights into Uly1040, an ulvan lyase from polysaccharide lyase family 40 [PDF]
Applied and Environmental MicrobiologyUlvan is a major polysaccharide in marine green algae. Its oligosaccharide degradation products possess diverse bioactivities and hold considerable potential for various applications.
Hou-Qi Wang +9 more
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Biocatalytic ulvan degradation by Pseudoalteromonas marina: exploring a marine polysaccharide bioconversion system [PDF]
Microbial Cell FactoriesUlvan depolymerization by marine bacteria is a specialized metabolic capability with significant implications for marine carbon cycling and biotechnological applications. While ulvan degradation systems have been extensively characterized in Bacteroidota,
Navindu Dinara Gajanayaka +10 more
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A twin xanthan lyase-dependent xanthan degradation system in Paenibacillus taichungensis I5 [PDF]
Applied Microbiology and BiotechnologyXanthan gum, a natural heteropolysaccharide produced by Xanthomonas species, has many biotechnological applications across industries due to its unique rheological properties.
Rui Han +6 more
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A novel exo-lytic and disaccharide-yielding glycosaminoglycan lyase from a marine-derived polysaccharide-degrading actinobacterium Microbacterium sp. strain WS15 [PDF]
Frontiers in MicrobiologyIntroductionGlycosaminoglycan (GAG) lyases play key roles in preparing oligosaccharides, treating human diseases, and learning relationships between complex structures and various functions of carbohydrates.
Peng Li +8 more
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Characterization of Alginate Utilization Strategy in a Novel Marine Bacteroidetes: Insights from Roseihalotalea indica gen. nov. sp. nov. TK19036T [PDF]
Marine DrugsAlginate, a major polysaccharide in brown algae, is vital for the carbon cycling of the ocean ecosystem and holds promise for biotechnological applications. Marine Bacteroidetes, known for the ability to degrade complex polysaccharides, play an important
Zheng Fu +5 more
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Insights into the mechanism of substrate specificity in a novel PL15_3 subfamily oligo-alginate lyase VBAly15A [PDF]
Applied and Environmental MicrobiologyAlginate is a major component of brown algae cell walls and can be degraded via β-elimination by alginate lyases. These enzymes are classified into polysaccharide lyases and oligo-alginate lyases (Oals), with Oals mainly represented by the PL15 and PL17 ...
Yongqi Tang +4 more
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Genes for degradation and utilization of uronic acid-containing polysaccharides of a marine bacterium Catenovulum sp. CCB-QB4 [PDF]
PeerJ, 2021 Background Oligosaccharides from polysaccharides containing uronic acids are known to have many useful bioactivities. Thus, polysaccharide lyases (PLs) and glycoside hydrolases (GHs) involved in producing the oligosaccharides have attracted interest in ...
Go Furusawa +2 more
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