Results 81 to 90 of about 29,286 (285)

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Identification and characterization of a critical loop for the high activity of alginate lyase VaAly2 from the PL7_5 subfamily

open access: yesFrontiers in Microbiology
As the major component in the cell wall of brown algae, alginates are degradable by alginate lyases via β-elimination. Alginate lyases can be categorized into various polysaccharide lyase (PL) families, and PL7 family alginate lyases are the largest ...
Muxuan Du   +5 more
doaj   +1 more source

Alginate Lyases: Sources, Mechanism of Activity and Potencial Application

open access: yesSqualen, 2013
Alginate lyases are group of enzymes which catalyze depolymerization of alginate into oligosaccharides. Alginate lyase have been widely used in many applications such as in production of bioactive oligosaccharides, control of polysaccharide rheological ...
Subaryono Subaryono   +3 more
doaj   +1 more source

Comparative Characterization of Aspergillus Pectin Lyases by Discriminative Substrate Degradation Profiling

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Fungal genomes often contain several copies of genes that encode carbohydrate active enzymes having similar activity. The copies usually have slight sequence variability, and it has been suggested that the multigenecity represents distinct reaction ...
Birgitte Zeuner   +5 more
doaj   +1 more source

Hydration of vinyl ether groups by unsaturated glycoside hydrolases and their role in bacterial pathogenesis [PDF]

open access: yes, 2008
Many pathogenic microorganisms invade mammalian and/or plant cells by producing polysaccharide-degrading enzymes (lyases and hydrolases). Mammalian glycosaminoglycans and plant pectins that form part of the cell surface matrix are typical targets for ...
Bunzo Mikami   +4 more
core   +2 more sources

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]

open access: yes, 2019
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn   +11 more
core   +2 more sources

Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis

open access: yesAdvanced Science, EarlyView.
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan   +8 more
wiley   +1 more source

Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum

open access: yesComputational and Structural Biotechnology Journal, 2014
Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The reverse of their natural reaction – the stereoselective addition of hydrogen cyanide (HCN) to carbonyls – yields chiral cyanohydrins, versatile building blocks for the ...
Romana Wiedner   +3 more
doaj   +1 more source

A bacterial symbiont in the gill of the marine scallop Argopecten irradians irradians metabolizes dimethylsulfoniopropionate

open access: yesmLife, 2023
Microbial lysis of dimethylsulfoniopropionate (DMSP) is a key step in marine organic sulfur cycling and has been recently demonstrated to play an important role in mediating interactions between bacteria, algae, and zooplankton.
Yi Shu   +12 more
doaj   +1 more source

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