Results 91 to 100 of about 21,937 (291)

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

One-pot asymmetric synthesis of chiral vicinal diols utilizing novel benzaldehyde lyases and carbonyl reductases

open access: yesGreen Synthesis and Catalysis
Chiral vicinal diols and their derivatives play pivotal roles in pharmaceutical chemistry and organic synthesis. However, their synthesis remains challenging due to the presence of adjacent chiral centers.
Xianqi Yin   +8 more
doaj   +1 more source

Diversity of Three-Dimensional Structures and Catalytic Mechanisms of Alginate Lyases

open access: yes, 2018
Alginate is a linear polysaccharide produced mainly by brown algae in marine environments. Alginate consists of a linear block copolymer made up of two monomeric units, β- d -mannuronate (M) and its C-5 epimer α- l
Peng Wang   +3 more
core   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Screening and identification of marine alginate lyase-producing bacteria and optimization of enzyme production conditions [PDF]

open access: yesZhongguo niangzao
Alginate lyases are mostly derived from marine bacteria with unique living environments. Using sodium alginate as the sole carbon source, a strain with high-yield alginate lyase from 56 strains of marine bacteria was screened using primary screening by ...
HU Mengdi, LI Yaozu, ZHANG Xiaoyong, MO Meiqing, GAO Xiangyang
doaj   +1 more source

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

open access: yesFood Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu   +6 more
wiley   +1 more source

Substrate Specificity of the Heparin Lyases from Flavobacterium heparinum

open access: yes, 1993
Archives of Biochemistry and Biophysics, 306, 461-468Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Linhardt, Robert J.   +2 more
core   +1 more source

Application, Challenges, and Prospects of Non‐Thermal Processing Technologies for Seaweed Protein Extraction—A Review

open access: yesFood Chemistry International, EarlyView.
This review highlights non‐thermal extraction technologies for seaweed proteins, emphasizing their mechanisms, impacts on protein structure and functionality, and sustainability potential. Key limitations related to species dependence, extract complexity, and scale‐up are discussed to guide future industrial and biorefinery applications.
Rahat Mahmud   +3 more
wiley   +1 more source

Insights into the mechanism of substrate specificity in a novel PL15_3 subfamily oligo-alginate lyase VBAly15A

open access: yesApplied and Environmental Microbiology
Alginate is a major component of brown algae cell walls and can be degraded via β-elimination by alginate lyases. These enzymes are classified into polysaccharide lyases and oligo-alginate lyases (Oals), with Oals mainly represented by the PL15 and PL17 ...
Yongqi Tang   +4 more
doaj   +1 more source

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