Results 91 to 100 of about 3,343 (218)
Pharmacological ResearchAggregation of TAR-DNA binding protein-43 (TDP-43) is a pathological feature present in nearly 97 % cases of amyotrophic lateral sclerosis (ALS), making it an attractive target for pathogenic studies and drug screening.
Jing Wen +12 more
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ChemistryOpen, Volume 14, Issue 6, June 2025.Sternbergia candida serves as a flexible reducing agent for the synthesis of SeNPs utilizing an economical and ecologically safe extract. Applications of selenium have demonstrated that plants cultivated in salinity preserve proper osmotic conditions and minimize cellular damage, as evidenced by photosynthetic pigments, proline, and MDA data.
Senem Kanber +2 more
wiley +1 more source
Galanthus woronowii (amaryllidaceae)'nin antioksidan aktivitesi ve toplam fenolik içeriği [PDF]
, 2019 Plants have been used for medicinal purpose since ancient times. Due to the including bioactive secondary metabolites, plants have gained the great interest for drug discovery and development process.
Eminağaoğlu, Özgür +2 more
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Cholinesterase-inhibitory effect and in silico analysis of alkaloids from bulbs of Hieronymiella species [PDF]
, 2018 Background In Argentina, the Amaryllidaceae family (59 species) comprises a wide variety of genera, only a few species have been investigated as a potential source of cholinesterases inhibitors to treat Alzheimer disease (AD).
Agüero, María Belén +9 more
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Novel Lycorine Derivatives as Anticancer Agents: Synthesis and In Vitro Biological Evaluation
Molecules, 2014 Lycorine, which is the most abundant alkaloid isolated from the Amaryllidaceae family of plants, reportedly exhibits promising anticancer activities.
Peng Wang +5 more
doaj +1 more source
Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome [PDF]
, 2016 Tumors can develop a blood supply not only by promoting angiogenesis but also by forming vessel-like structures directly from tumor cells, known as vasculogenic mimicry (VM).
Bonder, C. +14 more
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Analysis of Amaryllidaceae Alkaloids from by GC-MS and their Cholinesterase Activity
Natural Product Communications, 2011 The underivatized alkaloid mixture extracted from the bulbs of Chlidanthus fragrans Herb. was investigated by capillary GC/MS for the first time. Fifteen known Amaryllidaceae alkaloids of five structure types were identified.
Lucie Cahlíková +6 more
doaj +1 more source
Department of Metabolic Engineering [PDF]
, 2002 薬物代謝工学部門は和漢薬の薬効，毒性発現に関与する代謝系の分子生物学的研究を発展させることを設置目的とし，①和漢薬の薬効発現に関与する腸内細菌遺伝子の解析，②薬物代謝機能調節遺伝子の解明とその応用，③腎毒性物質産生機構の分子生物学的解明とその制御に関する研究を課題として取りあげ，和漢薬の薬効発現機構，生体へのレスポンスなどの基礎的研究を通じて，和漢薬の科学的評価や臨床応用をはかることを目指している。主な研究題目を以下に示す。1.
中村 憲夫 +3 more
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Zephgrabetaine: A New Betaine-type Amaryllidaceae Alkaloid from
Natural Product Communications, 2013 Zephgrabetaine (1), a new betaine type Amaryllidaceae alkaloid, along with seven known alkaloids, lycorine, galanthine, lycoramine, hamayne, haemanthamine, tortuosine, and ungeremine were isolated from the bulbs of Zephyranthes grandiflora and their ...
Deepali Katoch +6 more
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