Results 1 to 10 of about 253 (128)

Cytotoxicity Studies of Lycorine Alkaloids of the Amaryllidaceae [PDF]

open access: yesNatural Product Communications, 2014
The plant family Amaryllidaceae is renowned for its unique alkaloid constituents which possess a significant array of structural diversity. Several of these alkaloids are known for their interesting biological properties, of which galanthamine and ...
Jerald J Nair, J van Staden
exaly   +4 more sources

Advances in the Chemical and Biological Characterization of Amaryllidaceae Alkaloids and Natural Analogues Isolated in the Last Decade

open access: yesMolecules, 2020
Amaryllidaceae are bulbous wild and cultivated plants well known for their beautiful flowers and pharmaceutical applications, essentially due to the alkaloids and flavonoids content.
Marco Masi   +2 more
exaly   +3 more sources

Alkaloids from (Amaryllidaceae) [PDF]

open access: yesNatural Product Communications, 2013
In this study, the South African Amaryllid Boophone haemanthoides was examined for its phytochemical composition and cytotoxicity. In the process eight alkaloid structures, including the new compound distichaminol, were identified in bulb ethanolic ...
Jerald J. Nair   +4 more
doaj   +4 more sources

Mechanistic Insights to the Cytotoxicity of Amaryllidaceae Alkaloids [PDF]

open access: yesNatural Product Communications, 2015
With over 500 individual compounds, the Amaryllidaceae alkaloids represent a large and structurally diverse group of phytochemicals. Coupled to this structural diversity is the significant array of biological properties manifested by many of its members,
Jerald J. Nair   +4 more
doaj   +4 more sources

The Biological Activity of Alkaloids from the Amaryllidaceae: From Cholinesterases Inhibition to Anticancer Activity

open access: yesNatural Product Communications, 2016
Modern research has shown that Amaryllidaceae alkaloids represent a rich reservoir of potential small chemical molecules exhibiting several medicinal properties through various mechanisms.
Klara Habartová   +2 more
exaly   +2 more sources

Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids

open access: yesMolecules, 2020
Alkaloids are an important group of specialized nitrogen metabolites with a wide range of biochemical and pharmacological effects. Since the first publication on lycorine in 1877, more than 650 alkaloids have been extracted from Amaryllidaceae bulbous ...
Seydou Ka   +2 more
exaly   +3 more sources

Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids [PDF]

open access: yesMolecules, 2015
The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined.
Juan C. Cedrón   +4 more
doaj   +4 more sources

Carbohydrates stimulated Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum L. plants cultured in RITA® bioreactor [PDF]

open access: yesPeerJ, 2020
Background Leucojum aestivum L. is an important medicinal plant which produces Amaryllidaceae alkaloids, especially galanthamine and lycorine. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods ...
Agata Ptak   +6 more
doaj   +2 more sources

Recent Progress in Amaryllidaceae Biotechnology

open access: yesMolecules, 2020
Plants belonging to the monocotyledonous Amaryllidaceae family include about 1100 species divided among 75 genera. They are well known as medicinal and ornamental plants, producing pharmaceutically important alkaloids, the most intensively investigated ...
Vasil Georgiev   +2 more
doaj   +1 more source

Phytochemical and Biological Investigation of Narcissus pseudonarcissus Cultivated in Egypt [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences, 2018
A phytochemical investigation of the alkaloidal content of the bulbs of Narcissus pseudonarcissus cultivated in Egypt resulted in the isolation of the alkaloid; 9-O-demethyl-7-O-methyllycorenine (5) in addition to the eight known alkaloids; homolycorine (
Hiromitsu Takayama   +5 more
doaj   +1 more source

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