The Occurrence and Bioactivities of Amaryllidaceae Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review [PDF]
PlantsThe distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
G. David Lin +3 more
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Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity [PDF]
Plants, 2022 Clivia miniata (Amaryllidaceae) is an herbaceous evergreen flowering plant that is endemic to South Africa and Swaziland and belongs to one of the top-10 traded medicinal plants in informal medicine markets in South Africa.
Marcela Šafratová +9 more
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SWATH-MS-Based Proteomics Reveals the Regulatory Metabolism of Amaryllidaceae Alkaloids in Three Lycoris Species [PDF]
Int J Mol Sci, 2023 Alkaloids are a class of nitrogen-containing alkaline organic compounds found in nature, with significant biological activity, and are also important active ingredients in Chinese herbal medicine.
Youming Cai +9 more
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Molecules, 2020 Plants of the Amaryllidaceae family are promising therapeutic tools for human diseases and have been used as alternative medicines. The specific secondary metabolites of this plant family, called Amaryllidaceae alkaloids (AA), have attracted considerable
Darja Koutová +6 more
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A General Electro‐Synthesis Approach to Amaryllidaceae Alkaloids [PDF]
Chemistry – A European Journal, 2022 AbstractAmaryllidaceae alkaloids appeal to organic chemists with their attractive structures and their impressive antitumor and acetylcholinesterase inhibitory properties. We demonstrate a highly versatile access to this family of natural products. A general protocol with high yields in a sustainable electro‐organic key transformation on a metal‐free ...
Dennis Pollok +4 more
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Amaryllidaceae Alkaloids and Phenolic Acids Identification in Leucojum aestivum L. Plant Cultures Exposed to Different Temperature Conditions [PDF]
MoleculesAmaryllidaceae alkaloids are of notable pharmacological relevance. For instance, galanthamine is used in the treatment of Alzheimer’s disease, while other alkaloids (lycorine, crinine, etc.) derived from Amaryllidaceae plants are also of great interest ...
Agata Ptak +7 more
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Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity [PDF]
Parasit Vectors, 2021 Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected disease that afects ~7 million people worldwide. Development of new drugs to treat the infection remains a priority since those currently available have frequent side ...
Martinez-Peinado, Nieves +6 more
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Journal of Pharmacy and Bioallied Sciences, 2018 Background: Plants of the Amaryllidaceae family have been under intense scrutiny for the presence of a couple of alkaloidal secondary metabolites with endued cytotoxic activity, such as pancratistatin (1), 7-deoxypancratistatin (2), narciclasine (3), 7 ...
Bashir A Yousef +4 more
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Chemistry and Biological Activity of Alkaloids from the Genus Lycoris (Amaryllidaceae)
Molecules, 2020 Lycoris Herbert, family Amaryllidaceae, is a small genus of about 20 species that are native to the warm temperate woodlands of eastern Asia, as in China, Korea, Japan, Taiwan, and the Himalayas.
Lucie Cahlíková +2 more
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Biosynthesis of the Amaryllidaceae alkaloids
Plant Science Today, 2014 Amaryllidaceae alkaloids (AAs) are a structurally diverse group of plant specialized metabolites with powerful biological activities. The medicinal properties of many AAs have been identified including the antitumor agent narciclasine and galanthamine, used for Alzheimer’s disease.
Aparna Singh, Isabel Desgagné-Penix
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