Results 41 to 50 of about 2,622 (201)

N-oxide alkaloids from Crinum amabile (Amaryllidaceae) [PDF]

, 2018
Natural products play an important role in the development of new drugs. In this context, the Amaryllidaceae alkaloids have attracted considerable attention in view of their unique structural features and various biological activities.
Bastida, Jaume, Tallini, Luciana Ruschel, Marcel Kaiser, José Angelo S. Zuanazzi, Tallini, Luciana R., Warley de Souza Borges, Viladomat, Francesc, Warley Borges, Laura Torras-Claveria, Luciana R. Tallini, Luciana R. Tallini, Zuanazzi, José Angelo S., Jaume Bastida, José Angelo S. Zuanazzi, Francesc Viladomat, Kaiser, Marcel, Luciana Tallini, Torras-Claveria, Laura, José Zuanazzi, Warley de Souza Borges, Borges, Warley de Souza, Zuanazzi, Jose Angelo Silveira   +21 more
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Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors

Proceedings, 2019
The subfamily Amaryllidoideae within of the Amaryllidaceae family has an exclusive group of compounds called Amaryllidaceae alkaloids. Galanthamine, the most known Amaryllidaceae alkaloid, is approved by the FDA as an inhibitor of the enzyme ...
Karina Sierra, Natalie Cortés, Luciana R. Tallini, Warley de S. Borges, Jean Paulo de Andrade, Jaume Bastida, Edison Osorio Durango   +6 more
doaj   +1 more source

Amaryllidaceae alkaloids

, 2020
Amaryllidaceae family plants are an offered source of tetrahydroisoquinoline alkaloids, named AA. Most Amaryllidaceae species have been cultivated, in many places around the world, for their ornamental applications and pharmaceutical properties. These pharmaceutical properties are owed to the presence of AA alkaloids, which have a wide range of ...
openaire   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source

Acetylcholinesterase Inhibition Activity of Hippeastrum papilio (Ravenna) Van Scheepen (Amaryllidaceae) Using Zebrafish Brain Homogenates

Life, 2023
The Amaryllidaceae family constitutes an interesting source of exclusive alkaloids with a broad spectrum of biological activity. Galanthamine, the most relevant one, has been commercialized for the palliative treatment of Alzheimer’s disease symptoms ...
Luciana R. Tallini, Camila Rockenbach da Silva, Tatiana Jung, Elen de Oliveira Alves, Samira Leila Baldin, Miriam Apel, Luis F. S. M. Timmers, Eduardo Pacheco Rico, Jaume Bastida, José Angelo S. Zuanazzi   +9 more
doaj   +1 more source

A Golgi‐localized N‐methyltransferase and reversible aldo–keto reductases coordinate dual terminal routes in galanthamine biosynthesis

The Plant Journal, Volume 126, Issue 6, June 2026.
Significant Statement This study identifies LaTMT2, a Golgi‐localized N‐methyltransferase, and three reversible aldo–keto reductases (LaAKR1 and LaAKR3) as key enzymes coordinating the dual terminal routes of galanthamine biosynthesis in Leucojum aestivum.
Basanta Lamichhane, Archana Niraula, Natacha Merindol, Sarah‐Eve Gélinas, Patrick Lagüe, Simon Ricard, Hugo Germain, Isabel Desgagné‐Penix   +7 more
wiley   +1 more source

Investigação fitoquímica e biológica da espécie: Esenbeckia leiocarpa Engl. [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.A investigação fitoquímica biomonitorada das cascas da espécie Esenbeckia leiocarpa confirmou a presença de ...
Horst, Heros
core  

Cholinesterase Inhibition Activity, Alkaloid Profiling and Molecular Docking of Chilean Rhodophiala (Amaryllidaceae)

Molecules, 2018
Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for the clinical treatment of Alzheimer’s disease. The chemistry and bioactivity of Chilean representatives of Rhodophiala genus from the family of Amaryllidaceae
Luciana R. Tallini, Jaume Bastida, Natalie Cortes, Edison H. Osorio, Cristina Theoduloz, Guillermo Schmeda-Hirschmann   +5 more
doaj   +1 more source

Escin Attenuates Amyloid Beta 1‐42‐Induced Oxidative Stress, Apoptosis, and Neuroinflammation in Neuron‐Like SH‐SY5Y Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
This study demonstrates that Escin pretreatment exerts potent neuroprotection against Aβ1‐42‐induced toxicity in differentiated SH‐SY5Y cells. By suppressing the NF‐κB inflammatory axis, mitigating oxidative stress, and inhibiting the apoptotic cascade, Escin provides a mechanistic basis for its potential as a therapeutic candidate for Alzheimer's ...
Sakine Akar, Ozge Alvur, Gulsah Evyapan, Berna Ozdem, Ilknur Porsuk Doru   +4 more
wiley   +1 more source

Chemical evaluation and anticholinesterase activity of Hippeastrum puniceum (Lam.) Kuntz bulbs (Amaryllidaceae)

Brazilian Journal of Pharmaceutical Sciences, 2021
Hippeastrum puniceum is a species that belongs to the Amaryllidaceae family. A particular characteristic of this family is the consistent and very specific presence of isoquinoline alkaloids, which have demonstrated a wide range of biological activities ...
Letícia Carlesso Soprani, Jean P. de Andrade, Vanessa Dias dos Santos, Anderson Alves-Araújo, Jaume Bastida, Cristian A. Gasca Silva, Damaris Silveira, Warley de Souza Borges, Claudia Masrouah Jamal   +8 more
doaj   +1 more source