Results 51 to 60 of about 4,806 (212)
Brazilian Journal of Pharmaceutical Sciences, 2021 Hippeastrum puniceum is a species that belongs to the Amaryllidaceae family. A particular characteristic of this family is the consistent and very specific presence of isoquinoline alkaloids, which have demonstrated a wide range of biological activities ...
Letícia Carlesso Soprani +8 more
doaj +1 more source
Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]
, 2016 Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas +3 more
core +1 more source
, 2020 Amaryllidaceae family plants are an offered source of tetrahydroisoquinoline alkaloids, named AA. Most Amaryllidaceae species have been cultivated, in many places around the world, for their ornamental applications and pharmaceutical properties. These pharmaceutical properties are owed to the presence of AA alkaloids, which have a wide range of ...
openaire +1 more source
Flavonoid Oxime Carbamate Derivatives: Reversal of Multidrug Resistance in Cancer Cells
ChemMedChem, Volume 21, Issue 7, 14 April 2026.A set of 23 new flavonoid oxime carbamates was synthesized and evaluated as multidrug resistance (MDR) reversers in ABCB1‐transfected mouse lymphoma cells. All derivatives strongly inhibited P‐glycoprotein (P‐gp) efflux activity in a transport assay, while most selected compounds behaved as ATPase inhibitors. In drug combination assays, they interacted
Filipa Barbosa +5 more
wiley +1 more source
Molecules, 2018 Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for the clinical treatment of Alzheimer’s disease. The chemistry and bioactivity of Chilean representatives of Rhodophiala genus from the family of Amaryllidaceae
Luciana R. Tallini +5 more
doaj +1 more source
Metabolites, 2021 Alkaloids produced by the bulbs of the Amaryllidaceae are a source of pharmaceutical compounds. The main alkaloid, galantamine, is a reversible acetylcholinesterase inhibitor and allosteric nicotinic receptor modulator, which slows cognitive and ...
Dana Atrahimovich +4 more
doaj +1 more source
Antimicrobial, Antioxidant and Anti-Inflammatory Activities of the extract of a Moroccan endemic Narcissus: Narcissus broussonetii [PDF]
, 2017 The antioxidant, antibacterial and anti-inflammatory activities, of the extract of the Narcissus broussonetii bulbs were studied. The report concerning those properties of this Moroccan endemic species is described for the first time. Nine main alkaloids
Adly, Farida +11 more
core
Laboratory evaluation of natural and synthetic aromatic compounds as potential attractants for male mediterranean fruit fly, ceratitis capitata [PDF]
, 2019 Ceratitis capitata, the Mediterranean fruit fly, is one of the most serious agricultural pests worldwide responsible for significant reduction in fruit and vegetable yields. Eradication is expensive and often not feasible. Current control methods include
Cimmino, A. +7 more
core +1 more source
Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.ABSTRACT Due to limited access to, and the high cost of conventional veterinary services, Batswana communities often rely on ethnoveterinary practices for livestock health management. This review provides an in‐depth analysis on the ethnoveterinary uses, biological properties and safety assessment of plants utilised in livestock husbandry. A systematic
Tswelelopele G. Mpolokeng +7 more
wiley +1 more source
Natural AChE inhibitors from plants and their contribution to Alzheimer´s disease therapy [PDF]
, 2013 As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE activity.
Alza, Natalia Paola +4 more
core +2 more sources