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Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia.
Allen C. Steere+7 more
semanticscholar +8 more sources
A comprehensive genetic map of cytokine responses in Lyme borreliosis [PDF]
The incidence of Lyme borreliosis has risen, accompanied by persistent symptoms. The innate immune system and related cytokines are crucial in the host response and symptom development.
Javier Botey-Bataller+16 more
doaj +2 more sources
Comparative Study of Azithromycin versus Doxycycline for Treatment of Early [PDF]
Data from European and American authors concerning azithromycin efficacy in the treatment of Lyme borreliosis appear controversial. The aim of this study is to establish whether azithromycin is applicable to patients with early Lyme borreliosis. In these
I. Christova, R. Komitova
doaj +2 more sources
Lyme borreliosis is a multi-organ infection caused by spirochetes of the Borrelia burgdorferi sensu lato group with its species B burgdorferi sensu stricto, Borrelia garinii, and Borrelia afzelii, which are transmitted by ticks of the species Ixodes.
Curtis L. Fritz, Anne Kjemtrup
+10 more sources
Lyme disease (Lyme borreliosis) [PDF]
Lyme disease (Lyme borreliosis) has become the most common tick-borne disease in the northern hemisphere. Lyme disease was first described in 1977 by Steere et al. [1]. The town, Old Lyme, CT, USA, was the initial focus of an unusual cluster of juvenile rheumatoid arthritis.
Yasutake Yanagihara, Toshiyuki Masuzawa
openalex +3 more sources
Background The approach to surveillance of Lyme borreliosis varies between countries, depending on the purpose of the surveillance system and the notification criteria used, which prevents direct comparison of national data.
Emily MacDonald+9 more
doaj +2 more sources
Excess Healthcare Costs and Resource Utilisation of Lyme Borreliosis in Germany: A Propensity Score-Matched Cohort Study. [PDF]
ABSTRACT Aim Lyme borreliosis (LB) is the most common tick‐borne disease in Germany; however, data on the economic burden of LB are limited. In this study, we aim to report healthcare costs, healthcare resource utilisation (HCRU) and diagnostic consumption associated with LB by clinical manifestation.
Brestrich G+6 more
europepmc +2 more sources
Bridging the gap: Insights in the immunopathology of Lyme borreliosis. [PDF]
Lyme borreliosis is caused by Borrelia burgdorferi sensu lato transmitted by Ixodes ticks. The disease progresses from early localized infection to more severe conditions driven by ongoing inflammation. Understanding the role of Th1/Th2 balance, B‐cell dysfunction, and autoimmunity in Lyme borreliosis pathogenesis could improve diagnosis and treatment ...
Snik ME+3 more
europepmc +2 more sources
Diagnostic value of PCR analysis of synovial fluid for the diagnosis of Lyme borreliosis in dogs [PDF]
Lyme borreliosis, also known as Lyme disease, is a chronic multiorgan disease of humans and animals transmitted by ticks of the Ixodidae family and caused by a group of spirochetes Borrelia burgdorferi sensu lato.
Panteleienko O., Tsarenko T.
doaj +1 more source
Laboratory Diagnosis of Lyme Borreliosis
Lyme borreliosis is caused by a growing list of related, yet distinct, spirochetes with complex biology and sophisticated immune evasion mechanisms. SUMMARY Lyme borreliosis is caused by a growing list of related, yet distinct, spirochetes with complex ...
J. Branda, A. Steere
semanticscholar +1 more source