The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer +76 more
core +1 more source
Lyme disease (Lyme borreliosis) [PDF]
Lyme disease (Lyme borreliosis) has become the most common tick-borne disease in the northern hemisphere. Lyme disease was first described in 1977 by Steere et al. [1]. The town, Old Lyme, CT, USA, was the initial focus of an unusual cluster of juvenile rheumatoid arthritis.
Y, Yanagihara, T, Masuzawa
openaire +2 more sources
New insights into Lyme disease
Lyme borreliosis is transmitted through the bite of a tick that is infected by the bacterial spirochete Borrelia burgdorferi. Clinical manifestation of the disease can lead to heart conditions, neurological disorders, and inflammatory disorders ...
Brandon N. Peacock +3 more
doaj +1 more source
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
A rare cause of peripheral facial paralysis in childhood in our country: lyme disease [PDF]
Lyme disease is a zoonosis caused by Spirochetes called Borrelia burgdorferi, involving several areas, such as the skin, heart and central nervous system.
Gürses, Dolunay, Özdemir, Emine
core +2 more sources
Physician reported incidence of early and late Lyme borreliosis
Background Lyme borreliosis is the most common vector-borne disease in Europe and North America. The objective of this study is to estimate the incidence of tick bites and Lyme borreliosis, representative of our entire country, including erythema migrans,
Agnetha Hofhuis +4 more
doaj +1 more source
The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis [PDF]
Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia, respectively.
Bordignon, Valentina +10 more
core +2 more sources
Mini erythema migrans - A sign of early Lyme borreliosis [PDF]
Background: An erythema migrans (EM) remaining smaller than 5 cm in diameter, called mini EM by us, has not been addressed in detail. Objective: To study the significance of the mini EM as a sign of Lyme borreliosis. Methods: Patients with suspected mini
Weber, K., Wilske, B.
core +1 more source
Objective: The diagnosis of Lyme borreliosis is based on two-tier testing using an ELISA and Western blot. About 5–10% of patients report persistent symptoms of unknown etiology after treatment, resulting in substantial difficulties in further diagnostic
Foekje F. Stelma +5 more
doaj +1 more source
Modeling the effects of variable feeding patterns of larval ticks on the transmission of Borrelia lusitaniae and Borrelia afzelii [PDF]
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus
Bertolotti, Luigi +5 more
core +2 more sources

