Results 101 to 110 of about 1,206,897 (338)
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Serum and lymph lipids in rabbits with carbon tetrachloride-induced cirrhosis of the liver
Journal of Lipid Research, 1967 Lymph flow and the composition of lymph lipids from the hepatic and thoracic ducts of rabbits with cirrhosis of the liver (induced by 46-51 intramuscular injections of a mixture of carbon tetrachloride and olive oil at 4-day intervals) have been compared
Masahiko Kotani +5 more
doaj
Apolipoprotein M expression modifies the sphingolipid landscape in murine blood and lymph
Frontiers in ImmunologyMembers of the diverse family of sphingolipids (SPL), such as ceramides (Cer) and sphingomyelins (SM), are well-known structural and bioactive signaling molecules.
Victoria A. Blaho, Joshua T. Minyard
doaj +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Transfer of locally synthesized cholesterol from intestinal wall to intestinal lymph
Journal of Lipid Research, 1968 The cholesterol-fed rat subjected to cannulation of the intestinal lymph duct and injected with acetate-2-14C has been utilized for a study of the mechanism by which cholesterol synthesized in the intestinal wall gains access to the circulation.
Jean D. Wilson, Robert T. Reinke
doaj
Unexpected Metastasis of High Grade Serous Ovarian Cancer to Breast: Case Report and Literature Review [PDF]
, 2016 Introduction: Metastasis of ovarian serous carcinoma to breast and/or axillary lymph nodes represents an unusual event. Nevertheless, their detection and distinction from mammary carcinoma are of huge clinical importance because the treatment and ...
Colagiovanni, V +8 more
core +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells
Frontiers in Immunology, 2019 Until a few years ago, lymphatic vessels and lymphatic endothelial cells (LEC) were viewed as part of a passive conduit for lymph and immune cells to reach lymph nodes (LN).
Laura Santambrogio +2 more
doaj +1 more source
Combining mammaglobin and carcinoembryonic mRNA markers for early detection of micrometastases from breast cancers - a molecular study of 59 patients [PDF]
, 2006 Introduction: As many as 30% of node-negative breast cancer patients relapse within five years, suggesting that current histological detection methods are inadequate for identifying metastatic disease. Detecting small number of cancer cells in the breast
Dastan, J. +8 more
core