Results 101 to 110 of about 720,622 (316)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Mass kinetics of apolipoprotein A-I in interstitial fluid after administration of intravenous apolipoprotein A-I/lecithin discs in humans

open access: yesJournal of Lipid Research, 2006
Apolipoprotein kinetics are customarily determined by modeling time curves of specific radioactivity or isotopic enrichment in plasma after intravenous infusion of radiolabeled lipoproteins or stable isotope-enriched amino acids.
Roman Hovorka   +5 more
doaj  

SDF-Net: A Hybrid Detection Network for Mediastinal Lymph Node Detection on Contrast CT Images [PDF]

open access: yesarXiv
Accurate lymph node detection and quantification are crucial for cancer diagnosis and staging on contrast-enhanced CT images, as they impact treatment planning and prognosis. However, detecting lymph nodes in the mediastinal area poses challenges due to their low contrast, irregular shapes and dispersed distribution.
arxiv  

Cluster-Based Learning from Weakly Labeled Bags in Digital Pathology [PDF]

open access: yesarXiv, 2018
To alleviate the burden of gathering detailed expert annotations when training deep neural networks, we propose a weakly supervised learning approach to recognize metastases in microscopic images of breast lymph nodes. We describe an alternative training loss which clusters weakly labeled bags in latent space to inform relevance of patch-instances ...
arxiv  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Enhancement of rat lymphatic lipid transport by glucose or amino acids ingestion

open access: yesPhysiological Reports, 2019
To elucidate the effect of simultaneously fed carbohydrate or protein on lipid absorption, lymphatic lipid transports in the rat intestine were observed with or without simultaneous feeding of glucose or amino acids. A lipid emulsion containing 40 μmol/h
Hiroshi Hayashi
doaj   +1 more source

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