Results 191 to 200 of about 2,128,818 (392)

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

open access: yesScience, 2018
E. Pereira   +14 more
semanticscholar   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

open access: yesAdvanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia   +29 more
wiley   +1 more source

Molecular profiling of primary renal diffuse large B-cell lymphoma unravels a proclivity for immune-privileged tropism

open access: yesBlood Advances
Axel Künstner   +15 more
doaj   +1 more source

Lymph node with central hypodensity. [PDF]

open access: yesJ Bras Pneumol
Marchiori E, Hochhegger B, Zanetti G.
europepmc   +1 more source

Loss of Fibronectin Fiber Tension in Glioblastoma is Associated with Microvascular Proliferations and Immune Cell Infiltration

open access: yesAdvanced Science, EarlyView.
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani   +6 more
wiley   +1 more source

Endothelioma of Lymph Nodes [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1932
openaire   +2 more sources

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin   +9 more
wiley   +1 more source

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