Results 191 to 200 of about 426,643 (265)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

The Effect of Neoadjuvant Treatment on the Number of Lymph Node Dissection and Prognosis in Locally Advanced Rectal Cancer and Other Factors Affecting Lymph Node Metastasis. [PDF]

Cureus
Ozluk KK, Karaman N.
europepmc   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Preoperative contrast-enhanced ultrasound combined with intra-lymph node methylene blue injection for sentinel lymph node identification: a minimally invasive sentinel lymph node biopsy tracing approach. [PDF]

Eur Radiol
Liu Y, Wu J, Zhang W, Wang T, Wu S, Zhou H, Zhou Y, Liu Y.   +7 more
europepmc   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Automated Lymph Node and Extranodal Extension Assessment Improves Risk Stratification in Oropharyngeal Carcinoma. [PDF]

J Clin Oncol
Ye Z, Mojahed-Yazdi R, Zapaishchykova A, Tak D, Mahootiha M, Pardo JCC, Zielke J, Zha Y, Guthier C, Tishler RB, Margalit DN, Schoenfeld JD, Haddad RI, Uppaluri R, Haibe-Kains B, Fuller CD, Naser M, Burtness BA, Aerts HJWL, Hoebers F, Kann BH.   +20 more
europepmc   +1 more source

Machine Learning for Lymph Node Metastasis Prediction in Early Gastric Cancer: A Comparative Analysis. [PDF]

Int J Med Sci
Chen Y, Bai K, Yang M, Ma C, Gao X, Xu G, Chen Y, Zhang R.   +7 more
europepmc   +1 more source

Clinical Impact of Multifocality and Bilaterality on Lymph Node Metastasis in Papillary Thyroid Microcarcinoma. [PDF]

Diagnostics (Basel)
Goran M, Buta M, Nikolic S, Santrac N, Jeftic N, Savkovic N, Raketic J, Kozomara Z, Medic-Milijic N, Cvetkovic A, Pavlovic S, Markovic I.   +11 more
europepmc   +1 more source