Results 231 to 240 of about 1,831,806 (317)
Comparative evaluation of negative lymph node count, positive lymph node count, and lymph node ratio in prognostication of survival following completely resection for non-small cell lung cancer: a multicenter population-based analysis. [PDF]
Huang Q+8 more
europepmc +1 more source
A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan+6 more
wiley +1 more source
Application of CT in predicting lymph node metastasis in cervical cancer and construction of a preoperative nomogram. [PDF]
Meng X+6 more
europepmc +1 more source
This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun+23 more
wiley +1 more source
Patterns of lymph node metastasis and treatment outcomes of parotid gland malignancies. [PDF]
Wang W+5 more
europepmc +1 more source
High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng+11 more
wiley +1 more source
A novel peptide targeting CCR7 inhibits tumor cell lymph node metastasis. [PDF]
Sun Y+11 more
europepmc +1 more source
Reprogramming the tumor immune microenvironment is crucial for transforming immune “cold” tumors into “hot” inflammatory tumors. The investigation reveals that the combination of ICAM‐1‐Dxd with B7‐H3‐CD3 bispecific antibodies not only demonstrates significant inhibitory effects on tumor growth and metastasis but also plays a vital role in ...
Shoubing Zhou+9 more
wiley +1 more source