Results 251 to 260 of about 2,128,818 (392)

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA

Advanced Science, EarlyView.
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li, Julian Aurelio Marschner, Yoshihiro Kusunoki, Ningxin Zhang, Xiaoxin Li, Hao Deng, Zhibo Zhao, Kanako Watanabe‐Kusunoki, Zhihui Zhu, Yan Xu, Stefanie Steiger, Maciej Lech, Katalin Susztak, Christian Schulz, Hans‐Joachim Anders   +14 more
wiley   +1 more source

Immunoglobulin-producing cells in human pericancerous lymph nodes [PDF]

, 1969
P Burtin, F Loisillier, D Buffe, M Guillerm, Éliane Gluckman   +4 more
openalex   +1 more source

Noninvasive detection of clinically occult lymph-node metastases in prostate cancer.

New England Journal of Medicine, 2003
M. Harisinghani, J. Barentsz, P. Hahn, W. Deserno, S. Tabatabaei, C. H. van de Kaa, J. J. de la Rosette, R. Weissleder   +7 more
semanticscholar   +1 more source

Developing a Personalized Cancer Nanovaccine Using Coxsackievirus‐Reprogrammed Cancer Cell Membranes for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni, Yasir Mohamud, Amrit Singh, Razieh Sadat Banijamali, Jeffrey Tang, Jingchun Zhang, Honglin Luo   +6 more
wiley   +1 more source

Predictors of Dermal Invasion and Sentinel Lymph Node Metastasis in Patients With Extramammary Paget's Disease Without Clinical Lymph Node Enlargement. [PDF]

J Dermatol
Horisaki K, Yoshikawa S, Omata W, Tsutsumida A, Kiyohara Y.   +4 more
europepmc   +1 more source

Lymph node fibroblastic reticular cells in health and disease

Nature reviews. Immunology, 2015
A. Fletcher, S. Acton, Konstantin Knoblich   +2 more
semanticscholar   +1 more source

PD‐L1‐Targeting Biomimetic Photoresponsive Thermosensitive Liposomes for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Tan et al. developed a platelet membrane‐coated, thermoresponsive liposome for targeted, light‐controlled delivery of fluorinated peptides that promotes programmed death‐ligand 1 degradation, induces tumor immunogenic cell death, suppresses solid tumors and metastases, and triggers durable immune memory, offering a promising strategy for peptide‐based ...
Manman Tan, Chengyu Shi, Guangyi Chi, Xinwan Su, Fangzhou Liu, Linyu Zhu, Guangqian Cheng, Xiangyi Chen, Meng Yu, Yijian Chen, Ying Wang, Yu Chen, ShuLing Yan, Wenfei Wu, Qingfeng Yan, Jianzhong Shao, Kai Wang, Xiangrui Liu, Min Zhou, Aifu Lin   +19 more
wiley   +1 more source

V-Notes Sentinel Lymph Node Staging for Endometrial Cancer: A Systematic Review. [PDF]

J Clin Med
Nădăban M, Balint O, Secoșan C, Furău AM, Olaru F, Pirtea L.   +5 more
europepmc   +1 more source

American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer.

Journal of Clinical Oncology, 2005
G. Lyman, A. Giuliano, M. Somerfield, A. Benson, D. Bodurka, H. Burstein, A. Cochran, H. Cody, S. Edge, S. Galper, J. Hayman, Theodore Kim, Cheryl L. Perkins, D. Podoloff, V. Sivasubramaniam, R. Turner, R. Wahl, D. Weaver, A. Wolff, E. Winer   +19 more
semanticscholar   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source