Results 261 to 270 of about 1,831,806 (317)

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

open access: yesAdvanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu   +12 more
wiley   +1 more source

Lymphocyte Trapping in Dog Popliteal Lymph Nodes

open access: green, 1968
Join D. Jankins   +2 more
openalex   +2 more sources

Predictive risk-scoring model for lateral lymph node metastasis in papillary thyroid carcinoma. [PDF]

open access: yesSci Rep
Guo Y   +13 more
europepmc   +1 more source

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell‐Derived Exosomes for Suppressing Tumor Progression and Metastasis

open access: yesAdvanced Science, EarlyView.
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang   +12 more
wiley   +1 more source

Colorectal cancer lymph node dissection and disease survival. [PDF]

open access: yesWorld J Gastrointest Surg
Morera-Ocon FJ   +3 more
europepmc   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

open access: yesAdvanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin   +3 more
wiley   +1 more source

Semiconducting Open‐Shell Radicals for Precise Tumor Activatable Phototheranostics

open access: yesAdvanced Science, EarlyView.
A versatile phototheranostics nanoplatform of tumor‐specific activatable semiconducting open‐shell radicals for precise chemodynamic/photodynamic therapy (CDT/PDT) guided by “Turn On” second near‐infrared (NIR‐II) window fluorescence imaging (FLI) and PA imaging (PAI) through molecular engineering strategies. Abstract Semiconducting open‐shell radicals
Jie Zhang   +8 more
wiley   +1 more source

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