Results 21 to 30 of about 455,114 (219)
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
: Extramedullary plasmacytomas (EMPs) are exceedingly rare in children and adolescents. We describe clinical, pathological, and molecular features of 13 patients with EMP in this age group (8 males and 5 females; age 3-18 years).
Ilske Oschlies +14 more
doaj +1 more source
Evaluation of the Efficacy of Combined Sentinel Lymph Node Biopsy Using Patent Blue Dye and Peripheral Lymph Node Biopsy in Management of Nodal Negative Early Breast Cancer [PDF]
Introduction: Sentinel node biopsy is now established as the standard care for women with breast cancer. Itsaccuracy has been validated through multiple clinical trials but with less morbidities than ALND such as pain,restriction of arm movement and ...
Mina Shenouda +3 more
doaj +1 more source
Analysis of risk factors and prognosis of 253 lymph node metastasis in colorectal cancer patients
Background This study aimed to explore potential risk factors for 253 lymph node metastasis, and to identify the prognostic impact of 253 lymph node metastasis in colorectal cancer patients.
Shidong Hu +9 more
doaj +1 more source
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
CD19 expression is preserved following CD19-directed monoclonal antibody therapy with tafasitamab
IntroductionThe potential risk of eliminating or reducing CD19 expression following CD19-targeted therapies has raised questions about the optimal treatment sequencing strategies for B-cell malignancies. This study assessed CD19 expression and mutational
Johannes Duell +10 more
doaj +1 more source

