Results 41 to 50 of about 527,446 (319)

Characterization of lymph node stromal cells during Treg-mediated tolerance [PDF]

open access: yes, 2013
Solid organs transplantation is therapy of choice for several human diseases. The success of this treatment is determined by the recipientÕs ability to prevent rejection.
Broggi, Maria Anna Sofia
core   +1 more source

Extramedullary plasmacytoma in children is a genetically distinct localized neoplasia curable by surgical resection

open access: yesBlood Advances
: Extramedullary plasmacytomas (EMPs) are exceedingly rare in children and adolescents. We describe clinical, pathological, and molecular features of 13 patients with EMP in this age group (8 males and 5 females; age 3-18 years).
Ilske Oschlies   +14 more
doaj   +1 more source

Intrapulmonary Lymph Nodes.

open access: yesInternal Medicine, 1994
We report two cases of intrapulmonary lymph nodes detected by a chest roentgenogram or CT scan. The first patient was a 61-year-old fisherman referred complaining of cough and hemosputum. Chest roentgenogram showed a subpleural small nodular shadow at the superior segment of the right lower lobe. Thoracotomy showed a small anthracotic lymph node.
KINOSHITA, Akitoshi   +8 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The use of Raman spectroscopy for the intra-operative assessment of axillary lymph nodes in breast cancer [PDF]

open access: yes, 2012
Breast cancer remains a significant cause of morbidity and mortality. Assessment of the axillary lymph nodes is part of the staging of the disease. Advances in surgical management of breast cancer have seen a move towards intra-operative lymph node ...
Horsnell, Jonathan
core  

Antitumor factors of draining lymph node cells of the mouse sensitized with ehrlich ascites tumor cells. I. Antitumor effect of subcellular factor

open access: yes, 1969
The regional lymph node cells of the mice sensitized with Ehrlich ascites tumor cells is known to possess a substance that shows antitumor activity on target cells (JTC-II cells). For the purpose to clarify the localization of this substance the regional
Nakashima, Youichi
core   +1 more source

Decellularized Lymph Nodes as Scaffolds for Tissue Engineered Lymph Nodes [PDF]

open access: yesLymphatic Research and Biology, 2015
The lymphatic system is commonly injured during cancer treatment. However, despite the morbidity of these injuries, there are currently no options for replacing damaged lymphatics. The purpose of this study was to optimize methods for decellularization of murine lymph nodes (LN) and to determine if these scaffolds can be used to tissue engineer lymph ...
Daniel A, Cuzzone   +4 more
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Prognostic importance of harvested lymph node number, metastatic lymph node number, and lymph node ratio in surgically managed laryngeal squamous cell carcinoma

open access: yesBrazilian Journal of Otorhinolaryngology, 2021
Introduction: Lymph node metastasis is a well-known prognostic factor for laryngeal carcinoma. However, current nodal staging systems provide limited information regarding prognosis.
Mehmet Akif Abakay   +2 more
doaj   +1 more source

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