Results 81 to 90 of about 2,128,818 (392)

Increased lymph node yield in colorectal cancer is not necessarily associated with a greater number of lymph node positive cancers [PDF]

, 2014
Peer reviewedPublisher ...
Aly, Omar, Loudon, Malcom A, Murray, Graeme I, O'Shea, Aisling, Parnaby, Craig N, Samuel, Leslie M   +5 more
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Characteristics of systematic lymph node dissection and influencing factors of sentinel lymph node biopsy using carbon nanoparticles in endometrial carcinoma: a single-center study

World Journal of Surgical Oncology, 2023
Background Carbon nanoparticles (CNPs) are a new tracer for lymph node mapping, which can quickly reach and develop lymph nodes through a lymphatic network.
Siqi Tao, Zhibang Zhang, Liling Li, Xiaorui Yuan, Hongliang Chen, Yongjing Zhang, Chun Fu   +6 more
doaj   +1 more source

Decellularized Lymph Nodes as Scaffolds for Tissue Engineered Lymph Nodes [PDF]

Lymphatic Research and Biology, 2015
The lymphatic system is commonly injured during cancer treatment. However, despite the morbidity of these injuries, there are currently no options for replacing damaged lymphatics. The purpose of this study was to optimize methods for decellularization of murine lymph nodes (LN) and to determine if these scaffolds can be used to tissue engineer lymph ...
Babak J. Mehrara, Daniel A. Cuzzone, Swapna Ghanta, Seth Z. Aschen, Nicholas J. Albano   +4 more
openaire   +3 more sources

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer? [PDF]

, 2013
Shear wave elastography (SWE) shows promise as an adjunct to greyscale ultrasound examination in assessing breast masses. In breast cancer, higher lesion stiffness on SWE has been shown to be associated with features of poor prognosis.
A Evans, A Evans, AK Witkiewicz, Alastair Thompson, AM O’Shea, Andrew Evans, C Hatzis, CA Purdie, Caroline O. Michie, Colin A. Purdie, D Regner, DO Cosgrove, ES Burnside, J Boughey, JH Youk, JL Vandergrift, JLB Bevilacqua, JM Chang, Kim Thomson, KR Levental, LC Chen, Lee B. Jordan, MW Conklin, N Houssami, National Research Ethics Service, NO Kandemir, P Farmer, Patsy Whelehan, Petra Rauchhaus, PF Qiu, PL Fitzgibbons, Sarah Vinnicombe, T Kuehn, TC Kwok, WA Berg   +34 more
core   +4 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

In vitro studies on tumor-specific immunity by using C3H mammary cancer-A cells. II. Specificity in growth-inhibition effect of lymph-node cells from sensitized animal on target cells [PDF]

, 1966
For purpose to study specificity in the growth inhibition effect of sensitized lymph-node cells on target cells, the regional lymph-node cells obtained from the truly isologous mouse previously inoculated with A strain cells (derived from C3H mouse ...
Satoh, Katuaki
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Histopathology of the Lymph Nodes [PDF]

Toxicologic Pathology, 2006
Lymph nodes function as filters of tissues and tissue fluids and are sites of origin and production of lymphocytes for normal physiological functions. As part of this normal function, they react to both endogenous and exogenous substances with a variety of specific morphological and functional responses.
openaire   +3 more sources

Assessment of lymph node involvement in colorectal cancer.

World Journal of Gastrointestinal Surgery, 2016
Lymph node metastasis informs prognosis and is a key factor in deciding further management, particularly adjuvant chemotherapy. It is core to all contemporary staging systems, including the widely used tumor node metastasis staging system.
Mark Ong, J. Schofield
semanticscholar   +1 more source