Results 101 to 110 of about 85,449 (310)

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Technetium-99-Guided Axillary Lymph Node Identification: A Case Report of a Novel Technique for Targeted Lymph Node Excision Biopsy for Node Positive Breast Cancer After Neoadjuvant Chemotherapy. [PDF]

J Med Cases, 2023
Copeland JE, Cherian CJ, Lyew MA.
europepmc   +1 more source

Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]

, 2015
There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu, A de Gramont, A O’Shea, A Sternberg, AC Berger, C MacKay, C N Parnaby, ED Courtney, F Cianchi, G I Murray, G Ramsay, GT Williams, H Ueno, HK Choi, J Betge, J Lykke, J Wang, L Bui, L Samuel, L Schiffmann, LH Sobin, M A Loudon, M Morris, N W Scott, NN Baxter, OH Sjo, P Quirke, R Rosenberg, R Rosenberg, SJ Moug, SL Chen, W Hohenberger   +31 more
core   +2 more sources

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Paradoxical reaction associated with cervical lymph node tuberculosis: predictive factors and therapeutic management

International Journal of Infectious Diseases, 2017
Objectives: The aims of this study were to determine predictive factors of paradoxical reaction in patients with cervical lymph node tuberculosis (TB) and to discuss the therapeutic management of this condition.
Houda Chahed, Hela Hachicha, Aida Berriche, Rim Abdelmalek, Azza Mediouni, Badreddine Kilani, Mohamed Ben Amor, Hanene Tiouiri Benaissa, Ghazi Besbes   +8 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer [PDF]

, 2014
FEN1 has key roles in Okazaki fragment maturation during replication, long patch base excision repair, rescue of stalled replication forks, maintenance of telomere stability and apoptosis.
Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abdel-Fatah, Abhik Mukherjee, Ajit Jadhav, Anton Simeonov, Bergh, Brown, Buterin, Carlos Caldas, Chin, Curtis, David J. Maloney, David M. Wilson, Devika Agarwal, Dorjbal Dorjsuren, Dorjsuren, Graham Ball, Guo, Henneke, Henneke, Hongmao Sun, Hothorn, Ian O. Ellis, Jennifer L. Illuzzi, Kim, Kim, Krause, Kucherlapati, Kucherlapati, Lam, Larsen, Larsen, Liu, McShane, Moggs, Nada Albarakati, Nikolova, Oscar M. Rueda, Paul Moseley, Pawitan, Rachel Abbotts, Roslin Russell, Sato, Schultz-Norton, Shen, Singh, Srinivasan Madhusudan, Stephen Chan, Sultana, Tarek M.A. Abdel-Fatah, van Pel, Vivek Mohan, Wu, Xu, Yang, Zheng, Zheng   +59 more
core   +2 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source