Results 61 to 70 of about 495,796 (366)

Mask the Unknown: Assessing Different Strategies to Handle Weak Annotations in the MICCAI2023 Mediastinal Lymph Node Quantification Challenge [PDF]

Machine.Learning.for.Biomedical.Imaging. 2 (2024)
Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node segmentation in the mediastinum.
arxiv   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Comparisons of histological features among primary oral squamous cell carcinomas before and after adjuvant chemotherapy and their lymph node metastatic cancer lesions after adjuvant chemotherapy

Journal of Dental Sciences, 2022
Background/purpose: Adjuvant chemotherapy has been used to control the primary oral squamous cell carcinoma (OSCC) size prior to surgical excision of the cancer.
Feng-Chou Cheng, Ling-Hsia Wang, Yi-Ping Wang, Julia Yu-Fong Chang, Chun-Pin Chiang   +4 more
doaj  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Lymph node harvesting after laparoscopic complete mesocolic excision colectomy in colon cancer with practical application of glacial acid, absolute ethanol, water, and formaldehyde solution: A prospective cohort study

SAGE Open Medicine
Objectives: Quality of surgery has recently become an essential topic in the prognosis of colon cancer. Complete mesocolic excision for colon cancer has recently gained popularity with high-quality surgery.
Minh Thao Nguyen, Cong Thuan Dang, Tran Bao Song Nguyen, Nguyen Cuong Pham, Dinh Duong Le, Minh Duc Pham, Huu Tri Nguyen, Dinh Tuan Dung Phan, Doan Van Phu Nguyen, Thanh Phuc Nguyen, Phuoc Vung Doan, Dinh Son Nguyen, Anh Vu Pham   +12 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Prognostic Impact of Skip Metastasis to the Lateral Lymph Nodes in Lower Rectal Cancer

Journal of the Anus, Rectum and Colon
Objectives: Some patients with lower rectal cancer develop “skip metastasis,” in which lymph node metastasis occurs in the lateral but not the mesenteric lymph nodes. However, the prognostic impact of skip metastasis is unclear.
Sono Ito, Yasuyuki Takamizawa, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +4 more
doaj   +1 more source

Local Excision of a Mucinous Adenocarcinoma of the Anal Margin (Extramammary Paget’s Disease) and Reconstruction with a Bilateral V-Y Flap

Case Reports in Surgery, 2019
The case of a 75-year-old female with invasive extramammary Paget’s disease of the anal margin, without involvement of the anal canal, is reported. The patient underwent wide local excision of the lesion with reconstruction with a double V-Y flap, a ...
Michele Pagnanelli, Paola De Nardi, Stefano Martella, Luca Caruso, Riccardo Rosati   +4 more
doaj   +1 more source

Domain adaptation strategies for cancer-independent detection of lymph node metastases [PDF]

arXiv, 2022
Recently, large, high-quality public datasets have led to the development of convolutional neural networks that can detect lymph node metastases of breast cancer at the level of expert pathologists. Many cancers, regardless of the site of origin, can metastasize to lymph nodes.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source