Results 101 to 110 of about 346,670 (346)

Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies

open access: yesBMC Cancer, 2020
Background Since body mass index (BMI) is a convincing risk factor for breast cancer, it is speculated to be associated with lymph node metastasis. However, epidemiological studies are inconclusive.
Junyi Wang   +4 more
doaj   +1 more source

Correlation between T stage and lymph node metastasis in rectal cancer treated with preoperative chemoradiotherapy

open access: yesTherapeutic Advances in Medical Oncology, 2022
Background: Depth of tumor is a risk factor for lymph node metastasis in rectal cancer, but impact of yield pathologic T (ypT) stage on lymph node involvement in rectal cancer remains unclear. The aim of this study was to evaluate the correlation between
Seijong Kim   +7 more
doaj   +1 more source

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer. [PDF]

open access: yes, 2015
PurposeLeucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a cancer stem cell marker and a down-stream target in Wnt/β-catenin signaling. In human papillary thyroid cancer (PTC), over activation of Wnt/β-catenin has been associated with
Diehl, Anna Mae   +4 more
core   +3 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Mandatory multidisciplinary approach for the evaluation of the lymph node status in rectal cancer [PDF]

open access: yes, 2018
Colorectal cancer is the third most frequently reported malignancy and also the third leading cancer-related cause of death worldwide. Lymph node evaluation, both preoperatively and postoperatively, represents an important aspect of the diagnosis and ...
Ciorbagiu, Mihai C.   +5 more
core   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

A case of synchronous cervical lymph node metastases from testicular and thyroid cancers showing mixed response to chemotherapy [PDF]

open access: yes, 2000
37歳.精巣腫瘍の治療中, 偶然甲状腺癌の合併が判明し摘出術を施行した.化学療法に反応せずに残存した病変に対しては, 組織型の違いもさることながら, 重複癌の可能性も考慮に入れる必要があると考えられたWe report a case of synchronous presentation of thyroid cancer and testicular seminoma with lymph node metastasis.
中根, 比呂志   +6 more
core  

Extent of surgery in cancer of the colon : is more better? [PDF]

open access: yes, 2015
Since the introduction of total mesorectal excision as the standard approach in mid and low rectal cancer, the incidence of local recurrence has sharply declined. Similar attention to surgical technique in colon cancer (CC) has resulted in the concept of
Ceelen, Wim, Willaert, Wouter
core   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Assessment of Risk Factors for Lymph Node Metastasis in Endometrial Cancer

open access: yesİstanbul Medical Journal, 2019
Introduction:To determine the clinical and pathologic factors that are risk factors for metastasis of the lymph nodes (pelvic and/or aortic lymph nodes) in cases who underwent staging surgery due to endometrial carcinoma.Methods:The clinical and ...
Emre Erdem Taş   +4 more
doaj   +1 more source

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