Results 111 to 120 of about 126,790 (258)
BMC Cancer, 2020 Background Since body mass index (BMI) is a convincing risk factor for breast cancer, it is speculated to be associated with lymph node metastasis. However, epidemiological studies are inconclusive.
Junyi Wang +4 more
doaj +1 more source
LGR5 is associated with tumor aggressiveness in papillary thyroid cancer. [PDF]
, 2015 PurposeLeucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a cancer stem cell marker and a down-stream target in Wnt/β-catenin signaling. In human papillary thyroid cancer (PTC), over activation of Wnt/β-catenin has been associated with
Diehl, Anna Mae +4 more
core +3 more sources
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Mandatory multidisciplinary approach for the evaluation of the lymph node status in rectal cancer [PDF]
, 2018 Colorectal cancer is the third most frequently reported malignancy and also the third leading cancer-related cause of death worldwide. Lymph node evaluation, both preoperatively and postoperatively, represents an important aspect of the diagnosis and ...
Ciorbagiu, Mihai C. +5 more
core +4 more sources
Advanced Healthcare Materials, EarlyView.A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming
Advanced Materials, EarlyView.Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung +6 more
wiley +1 more source
A case of synchronous cervical lymph node metastases from testicular and thyroid cancers showing mixed response to chemotherapy [PDF]
, 2000 37歳.精巣腫瘍の治療中, 偶然甲状腺癌の合併が判明し摘出術を施行した.化学療法に反応せずに残存した病変に対しては, 組織型の違いもさることながら, 重複癌の可能性も考慮に入れる必要があると考えられたWe report a case of synchronous presentation of thyroid cancer and testicular seminoma with lymph node metastasis.
中根, 比呂志 +6 more
core
Sentinel lymph node concept in gastric cancer with solitary lymph node metastasis
World Journal of Gastroenterology, 2004 To study the localization of the solitary metastases in relation to the primary gastric cancers and the feasibility of sentinel lymph node (SLN) concept in gastric cancer.Eighty-six patients with gastric cancer, who had only one lymph node involved, were regarded retrospectively as patients with a possible sentinel node metastasis, and the distribution
Li-Yang, Cheng +2 more
openaire +2 more sources
Advanced Robotics Research, EarlyView.An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu +10 more
wiley +1 more source