Results 101 to 110 of about 960,720 (290)

Intraparotid Lymph Node Metastasis and Survival in Parotid Malignancies

B-ENT, 2023
Objective: This study aimed to determine the incidence of intraparotid lymph node metastasis in parotid malignancies and its association with overall survival.
Watthana Duksukkaew, Kroonpong Iampenkhae, Worawat Rawangban, Napadon Tangjaturonrasme   +3 more
doaj   +2 more sources

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source

The influence of postoperative risk factors on patient survival and lymph node metastasis in cervical squamous cell carcinoma

BMC Cancer
Objective To investigate the influence of postoperative pathological factors (including variables not categorized as moderate - to - high - risk factors according to the Sedlis criteria) on the prognosis and lymph node metastasis of patients with ...
Xuerong Wang, Yong Liu, Yanhua Li, Qi An, Juan Lu, Xiaodong Han   +5 more
doaj   +1 more source

Sentinel lymph node concept in gastric cancer with solitary lymph node metastasis

World Journal of Gastroenterology, 2004
To study the localization of the solitary metastases in relation to the primary gastric cancers and the feasibility of sentinel lymph node (SLN) concept in gastric cancer.Eighty-six patients with gastric cancer, who had only one lymph node involved, were regarded retrospectively as patients with a possible sentinel node metastasis, and the distribution
Li-Yang, Cheng, Shi-Zhen, Zhong, Zong-Hai, Huang   +2 more
openaire   +2 more sources

Sublingual Lymph Node Metastasis in Early-Stage Floor of the Mouth Carcinoma [PDF]

, 2017
Sublingual lenf nodlarına metastaz oral kavite kanserlerinde çok nadirdir. Bu olgu sunumunda sublingual lenf nodu metastazı olan erken evre ağız tabanı kanserli bir olgu sunulmuştur. Sublingual lenf nodlarına metastaz oranları düşükse de, erken evre ağız
Göksel Turhal, Kaya, Isa, Ozturk, Kerem, Kerem Öztürk, Turhal, Goksel, İsa Kaya   +5 more
core   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Management of Multiple Mediastinal Lymph Node Metastasis in Synchronic Colorectal and Lung Carcinomas [PDF]

Metastasis of colorectal carcinomas to mediastinal lymph nodes is extremely rare. In this study, it is aimed to share our approach to mediastinal lymph nodes for treating colorectal carcinoma and lung carcinoma detected synchronously.
Büşra Özdemir Çiflik, Sebahattin Sefa Ermancık, Furkan Süral, Nevzat Kılıç, Koray Aydoğdu, Olcay Kandemir   +5 more
core   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source