Results 121 to 130 of about 278,243 (313)

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Multivariate analyses of risk factors for lymph node metastasis and upper lymph node metastasis in patients who had received NACT.

, 2015
Multivariate analyses of risk factors for lymph node metastasis and upper lymph node metastasis in patients who had received NACT.
Shuang Li (146392), Fangxu Tang (720336), Ting Hu (110925), Xiong Li (112522), Qiang Tian (46635), Ru Yang (429495), Yao Jia (429494), Qinghua Zhang (145923), Kecheng Huang (636531), Ding Ma (115288)   +9 more
core   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Prognostic significance of lymph node metastasis and lymphadenectomy in early-stage ovarian carcinosarcoma

, 2018
Wen-Peng Wang,1 Ning Li,1 Yuan-Yuan Zhang,1 Yu-Tao Gao,2 Yang-Chun Sun,1 Li Ge,1 Ling-Ying Wu1 1Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences ...
Wu LY, Zhang YY, Wang WP, Gao YT, Sun YC, Ge L, Li N   +6 more
core  

Extended lymph node dissection for rectal cancer with radiologically diagnosed extramesenteric lymph node metastasis.

, 2009
BACKGROUND: The purpose of this study is to review the clinical outcomes of patients who received extended lymph node dissection for radiologically diagnosed extramesenteric lymph node metastasis.
김남규, 이강영, 김진수, 임준석, 손승국, 조장환, 민병소   +6 more
core   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

Papillary Thyroid Carcinoma with Extensive Cervical Lymph Node Metastasis and Initial Retropharyngeal Lymph Node Metastasis: A Case Report and Literature Review

Ear, Nose & Throat Journal
Papillary thyroid carcinoma (PTC) is prone to regional lymph node metastasis, which is more common in central lymph nodes and lateral cervical lymph nodes, and retropharyngeal lymph node metastasis (RLNM) is extremely rare. A male with PTC presented with
Yudong Ning, Sheng Qin, Dingfen Zeng, Yuqiu Zhou, Linjie Ma, Man Jiang, Shaoxin Wang   +6 more
doaj   +1 more source

[Breast cancer and lymph node metastasis: relation of lymph node dimensions and metastasis].

Pathologica, 2000
The Authors have examined 1159 lymph nodes obtained from 64 cases of breast carcinoma to value the presence of a correlation between the insurgence of metastases and lymph node dimensions. Metastases were more frequent in larger lymph nodes. Nevertheless, metastases were also present in small (< 5 mm) or very small (< 2 mm) lymph nodes.
F, Cappello, E, Barresi, A, Martorana
openaire   +1 more source

Dysfunction of GPX3 correlated with lymph node metastasis.

, 2013
(A) Loss of GPX3 gene expression correlated with lymph node metastasis. (B) Increase in GPX3 methylation correlated with lymph node metastasis. (C) GPX3 copy number change did not correlate with lymph node metastasis.
Tian-Ling Hu (303370), Ze-Kuan Xu (303373), Barbara G. Schneider (303372), Wael El-Rifai (303374), Dun-Fa Peng (303369), Zheng Chen (49483)   +5 more
core   +1 more source