Results 91 to 100 of about 431,717 (262)

Ultrasound and Shear Wave Elastography for Distinguishing Benign and Malignant Axillary Lymph Nodes in Breast Cancer Patients

open access: yesActa Clinica Croatica
This study aimed to assess the diagnostic efficacy of ultrasound (US) and shear wave elastography (SWE) in distinguishing benign and malignant axillary lymph nodes in patients with breast cancer.
Cihan Kalkan   +3 more
doaj   +1 more source

Lymph node calcifications [PDF]

open access: yesJornal Brasileiro de Pneumologia, 2018
Edson Marchiori   +2 more
openaire   +3 more sources

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

The Comparative Study of Lymph Node Dissection by Video-assisted Thoracoscopic Surgery (VATS) and Conventional Lateral Incision Surgery

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective Although widely adopted, there is lack of comparative data for patients undergoing lymph node dissection in radical surgery of lung cancer by video-assisted thoracoscopic surgery (VATS) vs conventional lateral incision surgery ...
Qiang LI   +8 more
doaj  

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

open access: yesAdvanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

A Study on Lymph Node Distribution in the Main Lymph Node Area for Left-sided Colon Cancer

open access: yesJournal of the Anus, Rectum and Colon
Objectives: In advanced left-sided colorectal cancer, cutting the root of the inferior mesenteric artery (IMA) branching from the aorta is recommended for complete lymph node dissection. However, this procedure sometimes causes severe complications. This
Fumiki Koga   +11 more
doaj   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

Use of intraoperative luminescent methods for detecting affected lymph nodes in patients with complicated forms of colon cancer

open access: yesСучасні медичні технології
The issue of the volume of lymphatic dissection in patients with complicated forms of colon cancer and the possibility of using methods of intraoperative visualisation of the affected lymph nodes remains controversial.
M. A. Kubrak   +3 more
doaj   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

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