Results 101 to 110 of about 498,192 (310)

Predictive factors for non-sentinel lymph nodes affection in breast carcinoma--outcomes of a Czech multicenter study of sentinel lymph nodes

, 2015
The aim of the study was to assess positivity nonsentinel lymph nodes in patients with macro, micro and submicrometastases in sentinel lymph nodes and find predictive factors of positivity nonsentinel lymph nodes. Study was conducted at the Department of
Hovorková, Eva, Hornychová, Helena, Dvořáčková, Jana, Čegan, Martin, Třeška, Vladislav, Havlíček, Karel, Michal, Michal, Gatěk, Jiří, Hes, Ondřej, Kubala, Otakar, Tomanová, Radoslava, Zedníková, Ilona, Prokop, Jolanta, Buzrla, Petr, Červinka, Vladimír, Ňaršanská, Andrea, Vachtová, Monika, Hácová, Marie, Sůvová, Božena, Horáček, Jaroslav, Ryška, Aleš, Šťastný, Karel, Velecký, Josef, Záhora, Jiří, Dostalík, Jan, Rothröckel, Pavel, Vážan, Petr, Ostruszka, Petr, Šiller, Jiří   +28 more
core  

Computed tomography and magnetic resonance imaging evaluation of pelvic lymph node metastasis in bladder cancer

Chinese Journal of Cancer, 2018
Background Accurate evaluation of lymph node metastasis in bladder cancer (BCa) is important for disease staging, treatment selection, and prognosis prediction.
Yong Li, Feiyu Diao, Siya Shi, Kaiwen Li, Wangshu Zhu, Shaoxu Wu, Tianxin Lin   +6 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Magnetic-Resonance Spectroscopy Detects Cancer in Draining Lymph-Nodes

, 1993
The spread of cancer cells to draining lymph nodes is an important prognostic factor for many cancers and influences postoperative therapy in patients. Histopathology is used routinely to assess if lymph nodes contain metastases. There are, however, time
Mountford, C.E., Mackinnon, WB, Lean, C.L., Hancock, R., Mackinnon, W.B., Mountford, CE, Russell, P, Russell, P., Dowd, S, Dowd, S., Tattersall, M.H., Lean, CL, Tattersall, Mhn, Hancock, R   +13 more
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Contrast enhanced ultrasound of sentinel lymph nodes

, 2013
Sentinel lymph nodes are the first lymph nodes in the region that receive lymphatic drainage from a primary tumor. The detection or exclusion of sentinel lymph node micrometastases is critical in the staging of cancer, especially breast cancer and ...
De Molo, Chiara, Cui, XinWu, Ignee, Andre, Jedrzejczyk, Maciej, Dagmar Schreiber-Dietrich, Pirri, Clara, Chiara De Molo, Clara Pirri, Schreiber-Dietrich, Dagmar, XinWu Cui, Maciej Jedrzejczyk, Andre Ignee, Nielsen, Michael Bachmann, Christoph, Dietrich F., Michael Bachmann Nielsen, Dietrich F. Christoph   +15 more
core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Patterns of cytokine gene expression of naïve and memory T lymphocytes in vivo.

, 2002
Large-scale lymphocyte recirculation occurs only at the level of secondary lymphoid tissue. Cells enter lymph nodes via afferent lymph from the tissue and via arterioles from the blood. They exit only via the efferent duct.
Hopkins, John, Hunter, Nora, Bailey, S., Gossner, Anton   +3 more
core  

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source