Results 111 to 120 of about 498,192 (310)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

The Comparative Study of Lymph Node Dissection by Video-assisted Thoracoscopic Surgery (VATS) and Conventional Lateral Incision Surgery

Chinese Journal of Lung Cancer, 2010
Background and objective Although widely adopted, there is lack of comparative data for patients undergoing lymph node dissection in radical surgery of lung cancer by video-assisted thoracoscopic surgery (VATS) vs conventional lateral incision surgery ...
Qiang LI, Jintao HE, Xiang ZHUANG, Xiaojun YANG, Jiang ZHU, Tianpeng XIE, Ping XIAO, Xiang WANG, Hao RONG   +8 more
doaj  

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

ANTERIOR DIAPHRAGMATIC LYMPH NODES

, 2017
In evaluating patients for malignant disease, involved or uninvolved anterior diaphragmatic lymph nodes (ADLNs) may be observed at computed tomography (CT) evaluation of either the chest or abdomen.
Holbert, JM, Libshitz, I
core  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Distribution of the Lymph Nodes in Neck Dissection Materials: Pathological Analysis

, 2001
Objectives:To analyze the lymph nodes in various neck dissections based on pathological analysis.Material and Method:The neck specimens of 86 patients who underwent neck dissection for head and neck malignancies in the last 10 years were reviewed ...
Elif Ayanoğlu, Cüneyd Üneri, Selçuk İnanlı, Handan Kaya, Mehmet Ali Şehitoğlu, Alper Tutkun, Çağlar Batman   +6 more
core  

Ultrasound and Shear Wave Elastography for Distinguishing Benign and Malignant Axillary Lymph Nodes in Breast Cancer Patients

Acta Clinica Croatica
This study aimed to assess the diagnostic efficacy of ultrasound (US) and shear wave elastography (SWE) in distinguishing benign and malignant axillary lymph nodes in patients with breast cancer.
Cihan Kalkan, Ilkay Koray Bayrak, Mesut Ozturk, Ahmet Veysel Polat   +3 more
doaj   +1 more source

Lymph node calcifications [PDF]

Jornal Brasileiro de Pneumologia, 2018
Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti   +2 more
openaire   +3 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

A Study on Lymph Node Distribution in the Main Lymph Node Area for Left-sided Colon Cancer

Journal of the Anus, Rectum and Colon
Objectives: In advanced left-sided colorectal cancer, cutting the root of the inferior mesenteric artery (IMA) branching from the aorta is recommended for complete lymph node dissection. However, this procedure sometimes causes severe complications. This
Fumiki Koga, Fumihiko Fujita, Takefumi Yoshida, Kenichi Koushi, Naohiro Yoshida, Takahiro Shigaki, Kenji Fujiyoshi, Naoki Mori, Tomoya Sudou, Jun Akiba, Nobuya Ishibashi, Touru Hisaka   +11 more
doaj   +1 more source