Results 161 to 170 of about 1,864,749 (354)

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

open access: yesAdvanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen   +17 more
wiley   +1 more source

Sentinel lymph node biopsy in breast cancer: Validation study and comparison of lymphatic mapping techniques [PDF]

open access: diamond, 2014
Aleksandar Guzijan   +5 more
openalex   +1 more source

An Updated Review on the Emerging Role of Indocyanine Green (ICG) as a Sentinel Lymph Node Tracer in Breast Cancer [PDF]

open access: gold, 2023
Ιωάννα Ακρίδα   +5 more
openalex   +1 more source

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin   +16 more
wiley   +1 more source

P1.13-02 Should Aortic Lymph Nodes be Considered Hilar Lymph Nodes in Patients with Completely Resected NSCLC? A Multicenter Study [PDF]

open access: bronze, 2019
Necati Çıtak   +8 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Modulate the Course of Peritoneal Inflammation Through Metabolic and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
MSC‐EVs alleviate peritoneal inflammation and fibrogenesis by disrupting the H3K18la‐CCL2 axis and crosstalk between mesothelial cells and Ly6c2⁺ macrophages. Model cartoons are constructed using the Biorender website (https://www.biorender.com/), and a usage license is obtained. Abstract Peritoneal dialysis (PD), as a renal replacement therapy, relies
Qiang Huang   +12 more
wiley   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer

open access: yesJournal of the American Medical Association (JAMA), 2017
Babak Ehteshami Bejnordi   +68 more
semanticscholar   +1 more source

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