Results 141 to 150 of about 498,192 (310)

HIGH CONCENTRATION OF BILIRUBIN IN POST-NODAL LYMPH ASSOCIATED WITH RED BLOOD CELL CATABOLISM IN LYMPH NODES OF THE SHEEP

, 2017
Qualitative and quantitative analysis of post-nodal lymph of the sheep has shown that the distinct yellow colour of this fluid pool is due to the presence of relatively large amounts of bilirubin.
Shannon, AD, Quin, JW
core  

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

X-RAY OPACIFICATION OF HEPATIC LYMPH NODES FOLLOWING INTRAVENOUS INJECTION OF TANTALUM DUST

, 2017
Available methods for x-ray opacification of lymph nodes rely upon either an intraperitoneal or an intralymphatic injection of contrast material. Intraperitoneal injection leads to opacification of intrathoracic, internal mammary nodes while injection ...
Martelli, A, Dumont, AE
core  

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

THERMAL INJURY AND INDUCED THERMOTOLERANCE IN RAT LYMPH NODES

, 2017
Immersion of the rat's hind limb in water at 45°or 46°C for one hour caused a severe burn of the extremity,including the popliteal lymph node. Pretreatmentone day in advance at 45° C for 15 minutes or43° C for one hour prevented most of the damage ...
Eidinoff, H, Levine, S, Mandelbrot, A
core  

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

ACCIDENTAL VISUALIZATION OF MESENTERIC LYMPH NODES BY BIPEDAL LYMPHOGRAPHY

, 2017
A case is presented of mesenteric lymph nodes filling accidentally by bipedal lymphography. The radiographs were interpreted erroneously as pathologic; consequently the patient was treated with chemotherapy and radiotherapy.
Bastholt, L, Pfeiffer, P
core  

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

LYMPHOID CELL MIGRATION BETWEEN DISTANT LYMPH NODES IN MICE

, 2017
Migration, circulation and recirculation of lymphocytes are important features ofthe immunologically active system (review: 1). While the existence of such a cell traffic between various lympho-reticular organs via the lymph and blood stream is well ...
Slonecker, C, Molleyres, J, Stoner, RD, Cottier, H, Hess, MW, Schindler, R   +5 more
core  

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source