Results 161 to 170 of about 498,192 (310)

THE ROLE OF LYMPH NODES IN PANCREATIC EDEMA

open access: yes, 2017
The pressure in the afferent lymphatic of the in situ perfused peripancreatic (periportal) lymph node of dogs rises with the rate of fluid infusion. A 10 min infusion of 500 ml physiological saline into the superior pancreato-duodenal artery resulted in ...
Markara, GB, Papp, M, Varga, B
core  

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Number of Resected Lymph Nodes and Survival Status in Node-Negative Esophageal Squamous Cell Carcinoma: A Cohort Study

open access: yes
Yifei Lu,1,* Minhua Ye,2,* Dehua Ma,2 Yu Chen2 1Department of Cardiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, People’s Republic of China; 2Department of Thoracic Surgery, Taizhou Hospital of ...
Ye M, Lu Y, Chen Y, Ma D
core  

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

THE DEMONSTRATION OF THE LYMPH PATHWAYS IN THE HAEMOLYMPH NODES OF CATTLE, AND THEIR RELATIONSHIP TO THE LYMPHATIC SYSTEM

open access: yes, 2017
Improvements  in  the  morphological  demonstration of the lymph vessels in bovine haemolymph nodes were achieved  with  the help  of  vital  dyes (patent blue violet  and Japanese ink)  and  by  the  lympho­ kinetic effect of a drug.
Fabian, G
core  

Prognostic Value and Therapeutic Implications of MRI-Based Negative Lymph Nodes in Nasopharyngeal Carcinoma. [PDF]

open access: yesCancer Med
Lin ZQ   +12 more
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

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