Results 261 to 270 of about 747,978 (331)
Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai+7 more
wiley +1 more source
Neuroendocrine Carcinoma Presenting as Metastasis of Unknown Origin in Cervical Lymph Nodes: An Unwonted Case Report. [PDF]
Kath A, Handa P, Ganesan A, Batra N.
europepmc +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen+7 more
wiley +1 more source
Staging Aortopulmonary Lymph Nodes With Robotic-Assisted Bronchoscopy: A Case Report and Literature Review. [PDF]
Vaca-Cartagena BF+10 more
europepmc +1 more source
Lymphography in Metastatic Lymph Node Disease
J I Burn, Stanley P. Bohrer
openalex +1 more source
LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li+27 more
wiley +1 more source
Boosting mRNA cancer vaccine efficacy via targeting <i>Irg1</i> on macrophages in lymph nodes. [PDF]
Wei W+22 more
europepmc +1 more source
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu+15 more
wiley +1 more source