Results 51 to 60 of about 747,978 (331)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Management of internal iliac and obturator lymph nodes in mid-low rectal cancer

open access: yesWorld Journal of Surgical Oncology
In rectal cancer treatment, the diagnosis and management of lateral pelvic lymph nodes (LLN) are critical for preventing local recurrence. Over time, scholars have reached a consensus: when imaging suggests LLN metastasis, combining neoadjuvant ...
Tixian Xiao, Jianan Chen, Qian Liu
doaj   +1 more source

Clinical significance in the number of involved lymph nodes in patients that underwent surgery for pathological stage III-N2 non-small cell lung cancer

open access: yesJournal of Cardiothoracic Surgery, 2011
Purpose This study investigated whether the number of involved lymph nodes is associated with the prognosis in patients that underwent surgery for pathological stage (p-stage) III/N2 NSCLC.
Shimokawa Hidehiko   +7 more
doaj   +1 more source

Changes in the Cell Squad of Iliac Lymph Nodes of White Rats in Case of Longterm Influence of Nalbufin [PDF]

open access: yes, 2018
The article presents data on the change in the cellular composition of the lymph nodes of the white rats, males of reproductive age, who received intramuscular opioid analgesics - nalbuphine every day for six weeks.
Holovatskyi, A. (Andrew)   +1 more
core  

Lymph Drainage of the Mammary Glands in Female Cats [PDF]

open access: yes, 2006
The mammary gland is a common site of neoplasms in the female cat. All the malignant tumors metastasize to a lesser or a greater extent through the lymphatic system.
Raharison, Fidiniaina, Sautet, Jean
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Relationship of the number and size of superficial groin lymph nodes with the stage of secondary lymphatic edema [PDF]

open access: yes, 2016
PURPOSE: This study evaluated the relationships of the size and number of superficial groin lymph nodes with the lower limb lymphedema stage and thus examined the role of superficial lymphatic lymph nodes in secondary lymphedema development.
Hiramatsu, Yuji   +4 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Origin of lymph node-derived lymphocytes in human hepatic allografts [PDF]

open access: yes, 1989
Hepatic allograft-derived lymph nodes were examined in the post-transplant period on order to determine the origin of lymphocytes and structural elements of the lymph node.
Chen, K   +7 more
core   +1 more source

A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread [PDF]

open access: yes, 2012
The lymphatic network that transports interstitial fluid and antigens to lymph nodes constitutes a conduit system that can be hijacked by invading pathogens to achieve systemic spread unless dissemination is blocked in the lymph node itself.
Germain, R.   +4 more
core   +1 more source

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