Results 181 to 190 of about 26,475 (231)

Embryonic lymphangiogenesis

Cell and Tissue Research, 1999
About 8-9 decades ago the development of embryonic lymphatics was studied intensively. Since then our knowledge has not considerably increased in this field, and it is still unknown whether lymphatics are derived by sprouting from veins, de novo from lymphangioblasts, or by both mechanisms.
Wilting, Jörg   +2 more
openaire   +3 more sources

Thrombospondin 1 and 2 along with PEDF inhibit angiogenesis and promote lymphangiogenesis in intrahepatic cholangiocarcinoma.

Journal of Hepatology, 2021
BACKGROUND & AIMS Intrahepatic cholangiocarcinoma (iCCA) microenvironment is hypovascularized, with a prominent development of lymphatic vessels. This leads to a rapid cancer spread into regional lymph nodes and the liver parenchyma, precluding curative ...
G. Carpino   +14 more
semanticscholar   +1 more source

Exosomes derived from human umbilical cord mesenchymal stem cells regulate lymphangiogenesis via the miR-302d-3p/VEGFR3/AKT axis to ameliorate inflammatory bowel disease.

International Immunopharmacology, 2022
BACKGROUND Exosomes released from human umbilical cord mesenchymal stem cell (hucMSC-Ex) have been revealed to hold great potential for the development of new treatment approaches for various diseases, including inflammatory bowel disease (IBD ...
Lu Zhang   +8 more
semanticscholar   +1 more source

Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4- LYVE1 axis.

Vascular pharmacology, 2021
Tumor-induced lymphangiogenesis promotes tumor progression by generating new lymphatic vessels that helps in tumor dissemination to regional lymph nodes and distant sites.
Chinmayee Sethy   +4 more
semanticscholar   +1 more source

A Fisheye View on Lymphangiogenesis

2013
Zebrafish have been widely used to study vasculogenesis and angiogenesis, and the vascular system is one of the most intensively studied organ systems in teleosts. It is a little surprising, therefore, that the development of the zebrafish lymphatic network has only been investigated in any detail for less than a decade now.
van Impel, Andreas   +1 more
openaire   +2 more sources

Corneal angiogenesis and lymphangiogenesis

Current Opinion in Allergy & Clinical Immunology, 2012
The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth.Studies on mice have revealed that apart from haemangiogenesis, lymphangiogenesis can also differ markedly between several ...
Birgit, Regenfuss   +2 more
openaire   +2 more sources

Lymphangiogenesis in development and disease

Thrombosis and Haemostasis, 2007
SummaryThe lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with ...
Ruediger, Liersch, Michael, Detmar
openaire   +2 more sources

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