Results 281 to 290 of about 43,762 (300)
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Lymphangiogenesis and cancer metastasis

Nature Reviews Cancer, 2002
Lymphatic vessels are important for the spread of solid tumours, but the mechanisms that underlie lymphatic spread and the role of lymphangiogenesis (the growth of lymphatics) in tumour metastasis has been less clear. This article reviews recent experimental and clinico-pathological data indicating that growth factors that stimulate lymphangiogenesis ...
Steven A, Stacker   +4 more
openaire   +2 more sources

Molecular Regulation of Lymphangiogenesis

Annals of the New York Academy of Sciences, 2004
Abstract: The lymphatic vascular system is necessary for the return of extravasated interstitial fluid and macromolecules to the blood circulation, for immune defense, and for the uptake of dietary fats. Impaired functioning of lymphatic vessels results in lymphedema, whereas tumor‐associated lymphangiogenesis may contribute to the spread of cancer ...
Pipsa, Saharinen, Tatiana V, Petrova
openaire   +2 more sources

Mouse corneal lymphangiogenesis model

Nature Protocols, 2011
This protocol describes a powerful in vivo method to quantitatively study the formation of new lymphatic vessels in the avascular cornea without interference of pre-existing lymphatics. Implantation of 100 ng of lymphangiogenic factors such as vascular endothelial growth factor (VEGF)-A, VEGF-C or fibroblast growth factor-2, together with slow-release ...
Cao, Renhai   +7 more
openaire   +2 more sources

Molecular control of lymphangiogenesis

BioEssays, 2002
AbstractThe lymphatic vasculature plays a critical role in the regulation of body fluid volume and immune function. Extensive research into the molecular mechanisms that control blood vessel growth has led to identification of molecules that also regulate development and growth of the lymphatic vessels.
Megan E, Baldwin   +2 more
openaire   +2 more sources

Historical overview of lymphangiogenesis

Current Opinion in Immunology, 2018
The investigation of the lymphatic system has a very long and intriguing history, with several medical figures which brought important contributions. Work on the lymphatic system began in the 17th century, and by the beginning of the 19th century the anatomy of most of the lymphatic system had been described.
openaire   +3 more sources

A Fisheye View on Lymphangiogenesis

2013
Zebrafish have been widely used to study vasculogenesis and angiogenesis, and the vascular system is one of the most intensively studied organ systems in teleosts. It is a little surprising, therefore, that the development of the zebrafish lymphatic network has only been investigated in any detail for less than a decade now.
van Impel, Andreas   +1 more
openaire   +2 more sources

The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function

Nature Cell Biology, 2021
K. Koltowska   +22 more
semanticscholar   +1 more source

Molecular regulation of angiogenesis and lymphangiogenesis

Nature reviews. Molecular cell biology, 2007
R. Adams, K. Alitalo
semanticscholar   +1 more source

Ciliary Body Lymphangiogenesis

Ophthalmology, 2013
Ludwig M, Heindl   +3 more
openaire   +2 more sources

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