Results 41 to 50 of about 419,246 (294)

Prognostic Significance of Canine Mammary Tumor Histologic Subtypes: An Observational Cohort Study of 229 Cases [PDF]

open access: yes, 2017
Histopathology is considered the gold standard diagnostic method for canine mammary tumors. In 2011, a new histologic classification for canine mammary tumors was proposed.
Berlato, Davide   +3 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The Role of Lymphatic Vascular Function in Metabolic Disorders

open access: yesFrontiers in Physiology, 2020
In addition to its roles in the maintenance of interstitial fluid homeostasis and immunosurveillance, the lymphatic system has a critical role in regulating transport of dietary lipids to the blood circulation. Recent work within the past two decades has
Pieter R. Norden, Tsutomu Kume
doaj   +1 more source

Comparison of Various Kinds of Probes for Lymphedematous Limbs

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Summary:. Recently, there has been a growing interest in the use of lymphatic ultrasound in the preoperative investigation of lymphaticovenous anastomosis. The device used for the performance of lymphatic ultrasound varies among surgeons.
Hisako Hara, MD, PhD, Makoto Mihara, MD
doaj   +1 more source

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. [PDF]

open access: yes, 2013
Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and ...
Golab, J.   +6 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Stenting for obstructive iliac vein lesions

open access: yesVeins and Lymphatics, 2017
Endovenous stenting has supplanted open surgery as the treatment of choice for iliocaval obstruction. This review provides a brief overview of such obstructive pathology and an in-depth assessment of femoroilio- caval stenting.
Arjun Jayaraj, Seshadri Raju
doaj   +1 more source

A Mathematical Model for Lymphangiogenesis in Normal and Diabetic Wounds

open access: yes, 2015
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries.
Bianchi, Arianna   +2 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study [PDF]

open access: yes, 2019
Aim Women with adenomyosis are at higher risk of endometriosis recurrence after surgery. This study was to assess if the lymphatic vessel network drained from the uterus to near organs where endometriosis foci lied.
Bonaccorsi, G.   +6 more
core   +1 more source

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