Results 41 to 50 of about 512,900 (381)

Lymphatics and Inflammation

open access: yesCurrent Medicinal Chemistry, 2009
Inflammation is a local or systemic tissue reaction caused by external or internal stimuli with the objective to remove the noxa, inhibit its further dissemination and eventually repair damaged tissue. Blood vessels and perivascular connective tissue are important regulators of the inflammatory process.
Wilting, J.   +3 more
openaire   +4 more sources

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson   +10 more
doaj   +1 more source

Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study [PDF]

open access: yes, 2019
Aim Women with adenomyosis are at higher risk of endometriosis recurrence after surgery. This study was to assess if the lymphatic vessel network drained from the uterus to near organs where endometriosis foci lied.
Bonaccorsi, G.   +6 more
core   +1 more source

Podoconiosis, a neglected lymphatic tropical disease

open access: yesVeins and Lymphatics, 2020
Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical ...
Paolo Zamboni, Mirko Tessari
doaj   +1 more source

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

open access: yesNature Communications, 2017
Cerebrospinal fluid (CSF) has been commonly accepted to drain through arachnoid projections from the subarachnoid space to the dural venous sinuses. However, a lymphatic component to CSF outflow has long been known.
Qiaoli Ma   +3 more
semanticscholar   +1 more source

Fibroblast-Generated Extracellular Matrix Guides Anastomosis during Wound Healing in an Engineered Lymphatic Skin Flap

open access: yesBioengineering, 2023
A healthy lymphatic system is required to return excess interstitial fluid back to the venous circulation. However, up to 49% of breast cancer survivors eventually develop breast cancer-related lymphedema due to lymphatic injuries from lymph node ...
Alvis Chiu   +4 more
doaj   +1 more source

The discovery of lymphatic system as a turning point in medical knowledge: Aselli, Pecquet and the end of hepatocentrism [PDF]

open access: yes, 2017
In this paper, I would like to analyse the impact of the discovery of lymphatic system on the development of the modern conception of human body. The discovery of lymphatics, as that of blood circulation, has in fact questioned important tenets of Galen ...
Tonetti, Luca
core   +2 more sources

Nasopharyngeal lymphatic plexus is a hub for cerebrospinal fluid drainage

open access: yesNature
Cerebrospinal fluid (CSF) in the subarachnoid space around the brain has long been known to drain through the lymphatics to cervical lymph nodes1–17, but the connections and regulation have been challenging to identify.
Jin-Hui Yoon   +11 more
semanticscholar   +1 more source

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

open access: yesNature Communications, 2019
Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause severe deficits in meningeal lymphatic drainage that begin within hours and ...
Ashley C. Bolte   +12 more
semanticscholar   +1 more source

Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

open access: yesTranslational Neurodegeneration, 2019
Abnormal aggregation of brain α-synuclein is a central step in the pathogenesis of Parkinson’s disease (PD), thus, it is reliable to promote the clearance of α-synuclein to prevent and treat PD.
Wenyan Zou   +7 more
semanticscholar   +1 more source

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