Results 21 to 30 of about 251,837 (264)

3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish

Pharmaceuticals, 2021
Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vasculature, plays critical roles in disease, including in cancer metastasis and chronic inflammation.
Kazuhide S. Okuda, Mei Fong Ng, Nur Faizah Ruslan, Neil I. Bower, Dedrick Soon Seng Song, Huijun Chen, Sungmin Baek, Philip S. Crosier, Katarzyna Koltowska, Jonathan W. Astin, Pei Jean Tan, Benjamin M. Hogan, Vyomesh Patel   +12 more
doaj   +1 more source

Machine learning-based model to predict liposuction outcomes in unilateral breast cancer-related lymphedema

Frontiers in Oncology
BackgroundBreast cancer-related lymphedema (BCRL) is a common and disabling complication after breast cancer surgery, with substantial effects on limb function and quality of life.
Shuai Pang, Hao Dong, Zhetan Ren, Zhong Liu, Peilin Li, Yonghao Cui, Zixuan Yao, Song Xia, Wenbin Shen   +8 more
doaj   +1 more source

THE NECESSITY OF COMPRESSION GARMENTS IN MANAGING LYMPHEDEMA

Journal of Cancer Rehabilitation, 2022
Background Lymphedema affects millions of cancer patients and survivors in the United States (US). The consequences of inadequately treated lymphedema include physiological changes that signi cantly impact their quality of life.
Said Nafai, Deborah Crow, Elizabeth W. Stevens-Nafai, Heather Ferguson   +3 more
doaj   +1 more source

Podoconiosis, a neglected lymphatic tropical disease

Veins and Lymphatics, 2020
Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical ...
Paolo Zamboni, Mirko Tessari
doaj   +1 more source

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

Frontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi, Nada S. Ahmed, Joseph L. Horder, Sarah J. Storr, Andrew V. Benest   +4 more
doaj   +1 more source

Lymphatic Alterations Under Tattoos: Preliminary Reports of One Observational Study

Clinical, Cosmetic and Investigational Dermatology, 2023
Pierre Bourgeois,1– 4 Mirela Mariana Roman,5 Justine Schweicher,6 Pauline Lavoisier,6 Philippe Maquet,6 Clarence Karler,7 Mateusz Lizewski,8 Alessandro Fouarge,8 Nicolas Cuylits,8 Véronique del Marmol,1 Olivier Leduc6 1Service of Dermatology, Hospital ...
Bourgeois P, Roman MM, Schweicher J, Lavoisier P, Maquet P, Karler C, Lizewski M, Fouarge A, Cuylits N, del Marmol V, Leduc O   +10 more
doaj  

The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9

Molecular Medicine, 2018
Background For the study, we determine the potential biomarkers and uncover the regulatory mechanisms of lncRNA MALAT1 / miR-145 / SOX9 axis on the abilities of cell growth and cell metastasis of colorectal cancer.
Yuanlin Xu, Xihong Zhang, Xiufeng Hu, Wenping Zhou, Peipei Zhang, Jiuyang Zhang, Shujun Yang, Yanyan Liu   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

M2 macrophage−derived exosomes improves secondary lymphedema through cellular mitochondrial homeostasis regulation via the Keap1-Nrf2/mPTP axis

Frontiers in Immunology
BackgroundSecondary lymphedema leads to progressive tissue remodeling and immune dysregulation. Dysregulation of macrophage polarization critically influences pathological progression.
Jinli Ma, Jinli Ma, Jinli Ma, Luya Pu, Luya Pu, Luya Pu, Yundong Zhang, Yundong Zhang, Yundong Zhang, Baiao Wu, Baiao Wu, Baiao Wu, Rui Fei, Rui Fei, Rui Fei, Dongmei Han, Dongmei Han, Dongmei Han, Miao Hao, Miao Hao, Miao Hao, Jianshi Du, Jianshi Du, Jianshi Du   +23 more
doaj   +1 more source

Establishment and validation of an orthotopic brain metastasis tumor model in C57BL/6 mice [PDF]

PeerJ
As a key experimental method to study the pathogenesis of brain tumors, the establishment of standardized operation process for intracranial orthotopic tumor modeling is of great significance.
Jiong Liu, Tonghao Lin, Juan Wang, Jiayun Hao, Wencheng Wu, Zhixin Zheng, Haibin Ou, Yu Liu   +7 more
doaj   +2 more sources